Ana Pérez, Alejandro Rujano-Salinas, Lelis Bennett, Rafael Muñoz, Patricia Moreno-Garces, Josue Huartaja, Carlos Sanchez-Ramirez
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引用次数: 0
Abstract
Background: Side effects of third molar surgery include edema and pain. Photobiomodulation (PBM) therapy is a noninvasive technology that minimizes these symptoms.
Purpose: To evaluate the effects of PBM on the control of postoperative edema and pain in patients undergoing surgical removal of third molars.
Study design, setting, and sample: A split-mouth, double-blinded, placebo-controlled, randomized clinical trial was conducted at the Faculty of Dentistry, José Antonio Páez University. The study enrolled patients who required bilateral surgical extraction of the impacted and retained third molars in comparable anatomical positions. Patients with soft or hard tissue pathology or systemic inflammatory conditions that could compromise healing were excluded from the study.
Predictor variable: The exposure to PBM was a predictor variable. One side of the jaw was randomly assigned as the treatment side and the opposite side as the untreated or control side. The treatment side received PBM using a 980 nm diode laser immediately after surgery and at 24, 48, and 72 hours postoperatively.
Outcome variables: The primary outcome variables were edema and pain. Edema was measured using a visual analog scale (VAS) and facial measurements (using a measuring tape in maximum intercuspation). Pain was measured using only the VAS.
Covariates: The covariates included age, sex, skin phototype, and analgesic use.
Analyses: Two-way analysis of variance and repeated measures analysis of variance were used for comparative analysis. A P value <.05 was considered statistically significant.
Results: A total of 37 patients, including 12 males (32.4%) and 25 females (67.6%), with a mean age of 22.8 ± 3.6 years, completed the study. Perceived edema, measured using a 10-cm VAS, was significantly lower in the PBM group at 24 hours (6 ± 2 vs 8 ± 2; P < .001), 48 hours (5 ± 2 cm vs 7 ± 2; P < .001), and 72 hours (3 ± 2 vs 6 ± 2; P < .001). Pain scores were also significantly reduced in the PBM group at 24 hours (4 ± 3 vs 6 ± 3; P = .002), 48 hours (4 ± 3 vs 5 ± 2; P = .003), and 72 hours (2 ± 2 vs 4 ± 2; P = .004).
Conclusion: The use of PBM significantly reduced edema and pain after the third molar surgery compared with the control group.
背景：第三磨牙手术的副作用包括水肿和疼痛。光生物调节（PBM）治疗是一种非侵入性技术，可以最大限度地减少这些症状。目的：评价PBM对第三磨牙手术患者术后水肿和疼痛的控制效果。研究设计、环境和样本：jos安东尼奥Páez大学牙科学院进行了一项裂口、双盲、安慰剂对照、随机临床试验。该研究纳入了需要双侧手术拔除在相似解剖位置的阻生和保留第三磨牙的患者。有软组织或硬组织病变或全身性炎症可能影响愈合的患者被排除在研究之外。预测变量：PBM暴露是一个预测变量。下颌一侧被随机指定为治疗侧，另一侧为未治疗侧或对照侧。治疗侧在术后立即以及术后24、48和72小时使用980 nm二极管激光进行PBM治疗。结局变量：主要结局变量为水肿和疼痛。水肿采用视觉模拟量表（VAS）和面部测量（在最大间歇使用卷尺）测量。仅使用VAS测量疼痛。协变量：协变量包括年龄、性别、皮肤光型和止痛药的使用。分析：采用双向方差分析和重复测量方差分析进行比较分析。结果：共37例患者完成研究，其中男性12例（32.4%），女性25例（67.6%），平均年龄22.8±3.6岁。采用10cm VAS测量的感知水肿在24小时PBM组显著降低(6±2 vs 8±2；P < 0.001)， 48小时(5±2 cm vs 7±2 cm；P < 0.001)和72小时(3±2 vs 6±2；P < 0.001)。PBM组疼痛评分在24小时也显著降低(4±3 vs 6±3；P = .002)， 48小时(4±3 vs 5±2；P = 0.003)和72小时(2±2 vs 4±2；P = .004)。结论：与对照组相比，使用PBM可明显减轻第三磨牙术后的水肿和疼痛。
期刊介绍：
This monthly journal offers comprehensive coverage of new techniques, important developments and innovative ideas in oral and maxillofacial surgery. Practice-applicable articles help develop the methods used to handle dentoalveolar surgery, facial injuries and deformities, TMJ disorders, oral cancer, jaw reconstruction, anesthesia and analgesia. The journal also includes specifics on new instruments and diagnostic equipment and modern therapeutic drugs and devices. Journal of Oral and Maxillofacial Surgery is recommended for first or priority subscription by the Dental Section of the Medical Library Association.
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