Sensitive periods for the association between smoking initiation and later oral health-related quality of life

IF 4.8 2区医学 Q1 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of dentistry Pub Date : 2025-06-07 DOI:10.1016/j.jdent.2025.105893

Leandro Machado Oliveira , Natanael Machado de Oliveira , Andressa Trindade Walter , Thayná Regina Pelissari

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引用次数: 0

Abstract

Aim

To examine the association between the age of smoking initiation (SI) and oral health-related quality of life (OHRQoL) in individuals aged 50 and older.

Methods

This secondary analysis utilised data from never and current smokers (N = 7153 complete cases) participating in the second wave of the Brazilian Longitudinal Study of Ageing (ELSI-Brazil 2019–2021), a nationally representative cohort of community-dwelling individuals aged 50 years and over. OHRQoL was assessed using the Oral Impacts on Daily Performance (OIDP) questionnaire. Adjusted zero-inflated negative binomial regression models were employed to estimate mean ratios (MRs) for the association between the age of SI and overall OIDP scores.

Results

Compared to never smokers, individuals who initiated smoking at ages 15–19, 10–14, and 5–9 years exhibited 29 % (95 % CI: 1.10, 1.51), 28 % (95 % CI: 1.06, 1.55), and 46 % (95 % CI: 1.12, 1.90) higher OIDP mean scores, respectively. After adjusting for pack-year smoking history, only the association for those who started smoking at ages 5–9 years remained significant (MR = 1.44; 95 % CI: 1.06, 1.96).

Conclusion

SI at childhood and adolescence is associated with poorer OHRQoL later in life. The association observed in individuals who started smoking between ages 5 and 9 appears to be independent of the cumulative smoking exposure.

Clinical significance

Early childhood represents a sensitive period during which SI has enduring adverse effects on oral health in later life. Tobacco control policies should prioritise early-life interventions to mitigate long-term oral and systemic health risks.

查看原文本刊更多论文

开始吸烟与后来口腔健康相关生活质量之间关系的敏感期。

目的：探讨50岁及以上人群开始吸烟年龄（SI）与口腔健康相关生活质量（OHRQoL）之间的关系。方法：这项二次分析利用了参与巴西老龄化纵向研究（ELSI-Brazil 2019-2021）第二波研究的从不吸烟者和当前吸烟者（N = 7153例完整病例）的数据，这是一个全国代表性的50岁及以上社区居民队列。OHRQoL采用口腔对日常表现的影响（OIDP）问卷进行评估。采用调整后的零膨胀负二项回归模型来估计SI年龄与总体OIDP评分之间关联的平均比率（MRs）。结果：与从不吸烟者相比，在15-19岁、10-14岁和5-9岁开始吸烟的个体分别表现出29% （95% CI: 1.10, 1.51）、28% （95% CI: 1.06, 1.55）和46% （95% CI: 1.12, 1.90）的OIDP平均得分高。在调整了吸烟史后，只有那些在5-9岁开始吸烟的人的相关性仍然显著(MR = 1.44；95% ci: 1.06, 1.96)。结论：儿童期和青春期的SI与以后生活中较差的OHRQoL相关。在5到9岁之间开始吸烟的个体中观察到的这种关联似乎与累积吸烟暴露无关。临床意义：儿童早期是一个敏感时期，在此期间SI对以后的口腔健康有持久的不良影响。烟草控制政策应优先考虑生命早期干预措施，以减轻长期口腔和全身健康风险。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of dentistry 医学-牙科与口腔外科

CiteScore

7.30

自引率

11.40%

发文量

349

审稿时长

35 days

期刊介绍： The Journal of Dentistry has an open access mirror journal The Journal of Dentistry: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. The Journal of Dentistry is the leading international dental journal within the field of Restorative Dentistry. Placing an emphasis on publishing novel and high-quality research papers, the Journal aims to influence the practice of dentistry at clinician, research, industry and policy-maker level on an international basis. Topics covered include the management of dental disease, periodontology, endodontology, operative dentistry, fixed and removable prosthodontics, dental biomaterials science, long-term clinical trials including epidemiology and oral health, technology transfer of new scientific instrumentation or procedures, as well as clinically relevant oral biology and translational research. The Journal of Dentistry will publish original scientific research papers including short communications. It is also interested in publishing review articles and leaders in themed areas which will be linked to new scientific research. Conference proceedings are also welcome and expressions of interest should be communicated to the Editor.