Fruit type ingestion and risk of hepatic steatosis: Analysis from two national database 2017–2020

IF 2.6 Q3 NUTRITION & DIETETICS
Thanathip Suenghataiphorn , Narisara Tribuddharat , Pojsakorn Danpanichkul , Narathorn Kulthamrongsri
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引用次数: 0

Abstract

Introduction

Hepatic Steatosis is an intrahepatic fat accumulation and can lead to liver dysfunction, inflammation, and advanced forms of nonalcoholic fatty liver disease (NAFLD). Fruits have been explored as a possible beneficial factor for some individuals with metabolic-associated liver diseases, but the evidence regarding the specific relationship between fruit types and hepatic steatosis remains limited.

Methods

We examined the data from a nationwide cross-sectional study using the 2017–March 2020 National Health and Nutrition Examination Survey (NHANES) database and the Food Patterns Equivalents Database (FPED) database. Using controlled attenuation parameter scores to differentiate between S0 to S3, for participants aged 18 years and older, we employed multivariable logistic regression to determine the association between specific types of fruit intake (citrus fruits, non-citrus fruits, and fruit juice) and the presence of hepatic steatosis.

Results

A total of 7568 participants were included in our study. Hepatic steatosis was present in 63 % of our participants. The average age was 48.8 years, with 50 % being females. Patients who consumed at least 0.86 cup-equivalents of citrus fruits daily (adjusted odds ratio [aOR] 0.82, 95 % confidence interval [CI] (0.71, 0.94), p = 0.004) had lower odds of having hepatic steatosis, whereas intake of fruit juice and non-citrus fruits was not statistically significantly associated with hepatic steatosis.

Conclusion

Citrus fruit consumption was associated with reduced odds of having hepatic steatosis in this U.S. adult population. Additional investigations into the pathophysiology, as well as longitudinal studies, are required to understand this relationship further and establish causality.
水果类型摄入与肝脂肪变性风险:来自两个国家数据库2017-2020的分析。
肝脂肪变性是一种肝内脂肪堆积,可导致肝功能障碍、炎症和晚期非酒精性脂肪性肝病(NAFLD)。水果已经被认为是一些代谢相关肝病患者的可能有益因素,但关于水果类型与肝脏脂肪变性之间具体关系的证据仍然有限。方法:我们使用2017年至2020年3月全国健康与营养检查调查(NHANES)数据库和食物模式等同数据库(FPED)数据库检查了一项全国性横断面研究的数据。对于18岁及以上的参与者,我们使用控制衰减参数评分来区分50到S3,我们采用多变量逻辑回归来确定特定类型的水果摄入量(柑橘类水果、非柑橘类水果和果汁)与肝脂肪变性的存在之间的关系。结果:我们的研究共纳入了7568名参与者。63%的参与者存在肝脂肪变性。平均年龄为48.8岁,其中50%为女性。每天摄入至少0.86杯柑橘类水果的患者(校正优势比[aOR] 0.82, 95%可信区间[CI] (0.71, 0.94), p=0.004)患肝脂肪变性的几率较低,而摄入果汁和非柑橘类水果与肝脂肪变性没有统计学意义上的显著相关性。结论:在美国成年人中,柑橘类水果的摄入与肝脂肪变性的几率降低有关。需要对病理生理学以及纵向研究进行进一步调查,以进一步了解这种关系并确定因果关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Clinical nutrition ESPEN
Clinical nutrition ESPEN NUTRITION & DIETETICS-
CiteScore
4.90
自引率
3.30%
发文量
512
期刊介绍: Clinical Nutrition ESPEN is an electronic-only journal and is an official publication of the European Society for Clinical Nutrition and Metabolism (ESPEN). Nutrition and nutritional care have gained wide clinical and scientific interest during the past decades. The increasing knowledge of metabolic disturbances and nutritional assessment in chronic and acute diseases has stimulated rapid advances in design, development and clinical application of nutritional support. The aims of ESPEN are to encourage the rapid diffusion of knowledge and its application in the field of clinical nutrition and metabolism. Published bimonthly, Clinical Nutrition ESPEN focuses on publishing articles on the relationship between nutrition and disease in the setting of basic science and clinical practice. Clinical Nutrition ESPEN is available to all members of ESPEN and to all subscribers of Clinical Nutrition.
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