Cognitive and Personality Profiles of Patients With Chronic Trigeminal Neuralgia

IF 3.4 2区医学 Q1 ANESTHESIOLOGY

European Journal of Pain Pub Date : 2025-06-11 DOI:10.1002/ejp.70054

Anton Pashkov, Elena Filimonova, Azniv Martirosyan, Galina Moisak, Jamil Rzaev

{"title":"Cognitive and Personality Profiles of Patients With Chronic Trigeminal Neuralgia","authors":"Anton Pashkov, Elena Filimonova, Azniv Martirosyan, Galina Moisak, Jamil Rzaev","doi":"10.1002/ejp.70054","DOIUrl":null,"url":null,"abstract":"<div>\n \n \n <section>\n \n <h3> Background</h3>\n \n <p>Patients suffering from chronic pain are known to exhibit distinctive personality traits and impaired neuropsychological performance across various cognitive domains. However, there is currently a lack of comprehensive evidence regarding cognitive and behavioural functioning patterns in patients with trigeminal neuralgia.</p>\n </section>\n \n <section>\n \n <h3> Methods</h3>\n \n <p>In this study, we aimed to thoroughly characterise a range of psychological and neuropsychological variables in a sample of 73 patients and 34 healthy controls, and to assess their relationship with pain intensity and duration.</p>\n </section>\n \n <section>\n \n <h3> Results</h3>\n \n <p>Our findings revealed that patients with trigeminal pain scored significantly higher on measures of anxiety, depression, perceived stress, alexithymia, pain catastrophizing, harm avoidance and lower on the Self-transcendence subscale compared to healthy controls. Additionally, these patients demonstrated lower performance scores on tasks assessing working memory and verbal fluency. The regression model with Rey complex figure copy, backward digit span and perceived stress scores taken as predictors accounted for 32% of the pain intensity variance.</p>\n </section>\n \n <section>\n \n <h3> Conclusions</h3>\n \n <p>These findings may provide valuable insights for the development of personalised treatment plans for patients with trigeminal neuralgia, specifically targeting their unique personality traits and cognitive impairments.</p>\n </section>\n \n <section>\n \n <h3> Significance</h3>\n \n <p>Our work expands the current understanding of cognitive deficits and personality traits in patients with chronic facial pain. Furthermore, this study provides additional evidence that psychological and neuropsychological factors significantly contribute to the patients' perception of pain.</p>\n </section>\n </div>","PeriodicalId":12021,"journal":{"name":"European Journal of Pain","volume":"29 6","pages":""},"PeriodicalIF":3.4000,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Journal of Pain","FirstCategoryId":"3","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/ejp.70054","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"ANESTHESIOLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background

Patients suffering from chronic pain are known to exhibit distinctive personality traits and impaired neuropsychological performance across various cognitive domains. However, there is currently a lack of comprehensive evidence regarding cognitive and behavioural functioning patterns in patients with trigeminal neuralgia.

Methods

In this study, we aimed to thoroughly characterise a range of psychological and neuropsychological variables in a sample of 73 patients and 34 healthy controls, and to assess their relationship with pain intensity and duration.

Results

Our findings revealed that patients with trigeminal pain scored significantly higher on measures of anxiety, depression, perceived stress, alexithymia, pain catastrophizing, harm avoidance and lower on the Self-transcendence subscale compared to healthy controls. Additionally, these patients demonstrated lower performance scores on tasks assessing working memory and verbal fluency. The regression model with Rey complex figure copy, backward digit span and perceived stress scores taken as predictors accounted for 32% of the pain intensity variance.

Conclusions

These findings may provide valuable insights for the development of personalised treatment plans for patients with trigeminal neuralgia, specifically targeting their unique personality traits and cognitive impairments.

Significance

Our work expands the current understanding of cognitive deficits and personality traits in patients with chronic facial pain. Furthermore, this study provides additional evidence that psychological and neuropsychological factors significantly contribute to the patients' perception of pain.

查看原文本刊更多论文

慢性三叉神经痛患者的认知和人格特征

患有慢性疼痛的患者在不同的认知领域表现出独特的人格特征和受损的神经心理表现。然而，目前缺乏关于三叉神经痛患者认知和行为功能模式的综合证据。在这项研究中，我们旨在全面表征73名患者和34名健康对照者的一系列心理和神经心理学变量，并评估它们与疼痛强度和持续时间的关系。结果三叉神经痛患者在焦虑、抑郁、压力感知、述情障碍、疼痛灾难化、伤害回避等单项得分显著高于健康对照组，自我超越单项得分显著低于健康对照组。此外，这些患者在评估工作记忆和语言流畅性的任务中表现出较低的表现得分。以Rey复形拷贝、后向指距和知觉应激评分为预测因子的回归模型对疼痛强度方差的贡献率为32%。结论针对三叉神经痛患者独特的人格特征和认知障碍，为其个性化治疗方案的制定提供了有价值的见解。我们的工作扩展了目前对慢性面部疼痛患者认知缺陷和人格特征的理解。此外，本研究还提供了心理和神经心理因素显著影响患者疼痛感知的证据。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

European Journal of Pain 医学-临床神经学

CiteScore

7.50

自引率

5.60%

发文量

163

审稿时长

4-8 weeks

期刊介绍： European Journal of Pain (EJP) publishes clinical and basic science research papers relevant to all aspects of pain and its management, including specialties such as anaesthesia, dentistry, neurology and neurosurgery, orthopaedics, palliative care, pharmacology, physiology, psychiatry, psychology and rehabilitation; socio-economic aspects of pain are also covered. Regular sections in the journal are as follows: • Editorials and Commentaries • Position Papers and Guidelines • Reviews • Original Articles • Letters • Bookshelf The journal particularly welcomes clinical trials, which are published on an occasional basis. Research articles are published under the following subject headings: • Neurobiology • Neurology • Experimental Pharmacology • Clinical Pharmacology • Psychology • Behavioural Therapy • Epidemiology • Cancer Pain • Acute Pain • Clinical Trials.