The effect of a therapeutic dose of folic acid after bariatric surgery and its impact on mental well-being

IF 2.9 3区医学 Q3 ENDOCRINOLOGY & METABOLISM

Annales d'endocrinologie Pub Date : 2025-06-01 DOI:10.1016/j.ando.2025.101757

Natia Romashvili, Nino Chochnidze

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引用次数: 0

Abstract

Objective

This study will examine the role of folic acid in bariatric patients and its impact on psychological health. A mixed methods approach will be used to gain a deeper understanding of how this B9 regulation affects individuals’ attitudes, mental states, and behaviors. The results of this study aim to raise awareness of the value of B9 in long-term weight-related challenges and provide valuable information on health.

Methods

The study will utilize a mixed-methods approach, combining quantitative surveys with qualitative interviews to assess quality. The study was conducted in the bariatric surgery department of Aversi Clinic in 2021–2024. Sixty patients were divided into two groups. In the first group, folate levels were determined before surgery and during shortages treatment was started at 800 mcg per day, In the second group, B9 was not prescribed before surgery, so they did not take in a therapeutic dose for the first month.

Results

As a result of observation and data analysis, it was revealed that, In the first group of patients, 76%, who received therapeutic doses of B9, the postoperative period was calm, anxiety was not detected at a high rate; also, depression was detected in only four patients, and adherence to the post-bariatric diet and recommendations was high. In the group that did not receive folic acid, 63%, relatively high anxiety and depression were observed. As for the result, it was more or less satisfactory.

Conclusion

This study aspires to identify sustainable strategies for maintaining how B9 can play an important role in enhancing both physical and mental health, ultimately contributing to successful and enduring weight loss during surgery. Therefore, based on the data obtained, it can be assumed that the research design, which aimed to determine B9's role, was evident even in a small study; which also increased the achievement of treatment results and patient compliance.

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减肥手术后叶酸治疗剂量的影响及其对心理健康的影响

目的探讨叶酸在肥胖患者中的作用及其对心理健康的影响。将采用混合方法来深入了解B9调节如何影响个体的态度、精神状态和行为。本研究的结果旨在提高人们对B9在长期体重相关挑战中的价值的认识，并提供有价值的健康信息。方法本研究将采用混合方法，将定量调查与定性访谈相结合来评估质量。该研究于2021-2024年在averi诊所的减肥外科进行。60例患者分为两组。在第一组中，叶酸水平在手术前确定，在短缺期间，治疗开始时为每天800微克。在第二组中，术前未开B9处方，因此他们在第一个月没有服用治疗剂量。结果观察和资料分析显示，第一组患者（76%）接受B9治疗剂量，术后期平静，未检出焦虑的比例较高；此外，只有4名患者检测到抑郁症，并且对减肥后饮食和建议的依从性很高。在没有服用叶酸的一组中，63%的人出现了相对较高的焦虑和抑郁。至于结果，还算令人满意。结论：本研究旨在确定维持B9在增强身心健康方面发挥重要作用的可持续策略，最终有助于手术期间成功和持久的减肥。因此，根据所获得的数据，可以假设，旨在确定B9作用的研究设计即使在一个小的研究中也是明显的；这也增加了治疗效果的实现和患者的依从性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Annales d'endocrinologie 医学-内分泌学与代谢

CiteScore

4.40

自引率

6.50%

发文量

311

审稿时长

50 days

期刊介绍： The Annales d''Endocrinologie, mouthpiece of the French Society of Endocrinology (SFE), publishes reviews, articles and case reports coming from clinical, therapeutic and fundamental research in endocrinology and metabolic diseases. Every year, it carries a position paper by a work-group of French-language endocrinologists, on an endocrine pathology chosen by the Society''s Scientific Committee. The journal is also the organ of the Society''s annual Congress, publishing a summary of the symposia, presentations and posters. "Les Must de l''Endocrinologie" is a special booklet brought out for the Congress, with summary articles that are always very well received. And finally, we publish the high-level instructional courses delivered during the Henri-Pierre Klotz International Endocrinology Days. The Annales is a window on the world, keeping alert clinicians up to date on what is going on in diagnosis and treatment in all the areas of our specialty.