Masoumeh Taghilou , Vahid Ahmadi , Javad Mirnajafi-Zadeh
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引用次数: 0
Abstract
Optical neural recordings are label-free and non-toxic as compared to the other methods. We introduce a compact and reliable membrane activity detection sensor based on surface plasmon resonance (SPR) and optical grating. We utilized a fiber optic port to direct light to the optical grating, allowing us to avoid bulky optical setups. Commercial DVD serves as the optical grating, which is both cost-effective and of high quality. In this sensor, we place mouse hippocampal tissue on the Au-sputtered gratings, and by measuring the reflectance spectrum, we investigate the SPR wavelength shift. The introduction of a high-K+ aCSF solution allows us to easily observe the effect of cell depolarization on the SPR wavelength can easily be observed. The proposed sensor achieves a high sensitivity of 628.06 nm/RIU.
期刊介绍:
Sensing and Bio-Sensing Research is an open access journal dedicated to the research, design, development, and application of bio-sensing and sensing technologies. The editors will accept research papers, reviews, field trials, and validation studies that are of significant relevance. These submissions should describe new concepts, enhance understanding of the field, or offer insights into the practical application, manufacturing, and commercialization of bio-sensing and sensing technologies.
The journal covers a wide range of topics, including sensing principles and mechanisms, new materials development for transducers and recognition components, fabrication technology, and various types of sensors such as optical, electrochemical, mass-sensitive, gas, biosensors, and more. It also includes environmental, process control, and biomedical applications, signal processing, chemometrics, optoelectronic, mechanical, thermal, and magnetic sensors, as well as interface electronics. Additionally, it covers sensor systems and applications, µTAS (Micro Total Analysis Systems), development of solid-state devices for transducing physical signals, and analytical devices incorporating biological materials.