A sweet spot in myeloid cell pro-tumoral functions

IF 25.5 1区医学 Q1 IMMUNOLOGY

Immunity Pub Date : 2025-06-10 DOI:10.1016/j.immuni.2025.05.015

Gillian Dunphy, David Sancho

引用次数: 0

Abstract

The regulation of myeloid cell responses can determine tumor outcomes. In this issue of Immunity, Blidner et al. report that galectin-1 triggers both immunoregulatory and pro-angiogenic circuits in myeloid cells, promoting tumor growth via a VEGF-dependent mechanism.

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骨髓细胞促肿瘤功能的最佳点

髓细胞反应的调节可以决定肿瘤的预后。在这一期的《免疫》杂志上，Blidner等人报道了半乳糖凝集素-1在髓细胞中触发免疫调节回路和促血管生成回路，通过vegf依赖机制促进肿瘤生长。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Immunity 医学-免疫学

CiteScore

49.40

自引率

2.20%

发文量

205

审稿时长

6 months

期刊介绍： Immunity is a publication that focuses on publishing significant advancements in research related to immunology. We encourage the submission of studies that offer groundbreaking immunological discoveries, whether at the molecular, cellular, or whole organism level. Topics of interest encompass a wide range, such as cancer, infectious diseases, neuroimmunology, autoimmune diseases, allergies, mucosal immunity, metabolic diseases, and homeostasis.