{"title":"Supramolecular Assembly of Dendrobium officinale Polysaccharides-Hyaluronic Acid and Its Moisturizing Properties.","authors":"Hankun Ren, Taiju Di, Hong Meng, Peina Zha","doi":"10.1111/srt.70190","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Supramolecular technology has been widely applied in cosmetics due to its ability to enhance the stability of active substances and reduce their irritation potential. The synergistic interaction between polysaccharides can produce new products with characteristics and rheological properties that make them suitable for various applications.</p><p><strong>Objective: </strong>The supramolecularly assembly of Dendrobium officinale polysaccharide (DOP) and hyaluronic acid (HA) was produced, and its moisturizing effect was verified to provide a basis for the application of supramolecular technology in cosmetic functional raw materials.</p><p><strong>Methods: </strong>The supramolecular structure of polysaccharide assembly samples was verified through scanning electron microscopic observation. Moisture absorption and the ability of samples to resist cell drying damage before and after supramolecular assembly were evaluated by moisture absorption experiments and a cell drying damage model, respectively. Furthermore, this study validated the moisturizing effect of the supramolecular compositions during their application in cosmetics through tests of skin moisture content in extremely dry environments (during the winter season of Beijing, China), skin roughness and scale index, and trans epidermal water loss.</p><p><strong>Results: </strong>The supramolecular composition appeared as a large sheet-like structure under a scanning electron microscope. Further, the supramolecular composition had significantly improved moisture absorption performance and could effectively resist cell drying damage. In an extremely dry environment, the composition showed excellent moisturizing performance and effectively improved skin scale and roughness.</p><p><strong>Conclusions: </strong>The supramolecular assembly of DOP and HA has a synergistic moisturizing effect; thus, it can be expected to have a good moisturizing effect when applied to cosmetics.</p>","PeriodicalId":21746,"journal":{"name":"Skin Research and Technology","volume":"31 6","pages":"e70190"},"PeriodicalIF":3.2000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145926/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Skin Research and Technology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1111/srt.70190","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Supramolecular technology has been widely applied in cosmetics due to its ability to enhance the stability of active substances and reduce their irritation potential. The synergistic interaction between polysaccharides can produce new products with characteristics and rheological properties that make them suitable for various applications.
Objective: The supramolecularly assembly of Dendrobium officinale polysaccharide (DOP) and hyaluronic acid (HA) was produced, and its moisturizing effect was verified to provide a basis for the application of supramolecular technology in cosmetic functional raw materials.
Methods: The supramolecular structure of polysaccharide assembly samples was verified through scanning electron microscopic observation. Moisture absorption and the ability of samples to resist cell drying damage before and after supramolecular assembly were evaluated by moisture absorption experiments and a cell drying damage model, respectively. Furthermore, this study validated the moisturizing effect of the supramolecular compositions during their application in cosmetics through tests of skin moisture content in extremely dry environments (during the winter season of Beijing, China), skin roughness and scale index, and trans epidermal water loss.
Results: The supramolecular composition appeared as a large sheet-like structure under a scanning electron microscope. Further, the supramolecular composition had significantly improved moisture absorption performance and could effectively resist cell drying damage. In an extremely dry environment, the composition showed excellent moisturizing performance and effectively improved skin scale and roughness.
Conclusions: The supramolecular assembly of DOP and HA has a synergistic moisturizing effect; thus, it can be expected to have a good moisturizing effect when applied to cosmetics.
期刊介绍：
Skin Research and Technology is a clinically-oriented journal on biophysical methods and imaging techniques and how they are used in dermatology, cosmetology and plastic surgery for noninvasive quantification of skin structure and functions. Papers are invited on the development and validation of methods and their application in the characterization of diseased, abnormal and normal skin.
Topics include blood flow, colorimetry, thermography, evaporimetry, epidermal humidity, desquamation, profilometry, skin mechanics, epiluminiscence microscopy, high-frequency ultrasonography, confocal microscopy, digital imaging, image analysis and computerized evaluation and magnetic resonance. Noninvasive biochemical methods (such as lipids, keratin and tissue water) and the instrumental evaluation of cytological and histological samples are also covered.
The journal has a wide scope and aims to link scientists, clinical researchers and technicians through original articles, communications, editorials and commentaries, letters, reviews, announcements and news. Contributions should be clear, experimentally sound and novel.
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