{"title":"\"Target Sign\" of Schwannoma on Contrast Enhanced Ultrasound.","authors":"Lu Yang, Li-Gang Cui","doi":"10.1002/jum.16737","DOIUrl":null,"url":null,"abstract":"<p><p>This case series investigates the \"Target sign\" in contrast-enhanced ultrasound (CEUS) of 11 pathologically confirmed schwannomas, characterized by early central hyperenhancement (mean TTP: 15.7 ± 3.2 s) surpassing peripheral regions (19.1 ± 2.8 s). CEUS demonstrated 100% detection of this sign, outperforming grayscale ultrasound (45%), correlating with histologic Antoni A (cellular) and B (myxoid) areas. Findings suggest CEUS improves diagnostic specificity for schwannomas, offering non-invasive microvascular mapping. Limitations include small sample size and retrospective design.</p>","PeriodicalId":17563,"journal":{"name":"Journal of Ultrasound in Medicine","volume":" ","pages":""},"PeriodicalIF":2.1000,"publicationDate":"2025-06-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ultrasound in Medicine","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1002/jum.16737","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ACOUSTICS","Score":null,"Total":0}
引用次数: 0
Abstract
This case series investigates the "Target sign" in contrast-enhanced ultrasound (CEUS) of 11 pathologically confirmed schwannomas, characterized by early central hyperenhancement (mean TTP: 15.7 ± 3.2 s) surpassing peripheral regions (19.1 ± 2.8 s). CEUS demonstrated 100% detection of this sign, outperforming grayscale ultrasound (45%), correlating with histologic Antoni A (cellular) and B (myxoid) areas. Findings suggest CEUS improves diagnostic specificity for schwannomas, offering non-invasive microvascular mapping. Limitations include small sample size and retrospective design.
期刊介绍:
The Journal of Ultrasound in Medicine (JUM) is dedicated to the rapid, accurate publication of original articles dealing with all aspects of medical ultrasound, particularly its direct application to patient care but also relevant basic science, advances in instrumentation, and biological effects. The journal is an official publication of the American Institute of Ultrasound in Medicine and publishes articles in a variety of categories, including Original Research papers, Review Articles, Pictorial Essays, Technical Innovations, Case Series, Letters to the Editor, and more, from an international bevy of countries in a continual effort to showcase and promote advances in the ultrasound community.
Represented through these efforts are a wide variety of disciplines of ultrasound, including, but not limited to:
-Basic Science-
Breast Ultrasound-
Contrast-Enhanced Ultrasound-
Dermatology-
Echocardiography-
Elastography-
Emergency Medicine-
Fetal Echocardiography-
Gastrointestinal Ultrasound-
General and Abdominal Ultrasound-
Genitourinary Ultrasound-
Gynecologic Ultrasound-
Head and Neck Ultrasound-
High Frequency Clinical and Preclinical Imaging-
Interventional-Intraoperative Ultrasound-
Musculoskeletal Ultrasound-
Neurosonology-
Obstetric Ultrasound-
Ophthalmologic Ultrasound-
Pediatric Ultrasound-
Point-of-Care Ultrasound-
Public Policy-
Superficial Structures-
Therapeutic Ultrasound-
Ultrasound Education-
Ultrasound in Global Health-
Urologic Ultrasound-
Vascular Ultrasound