HIV and Pregnancy: Navigating Complex Decision Making and Preventing Perinatal Transmission.

IF 3.7 2区医学 Q2 INFECTIOUS DISEASES

Current HIV/AIDS Reports Pub Date : 2025-06-07 DOI:10.1007/s11904-025-00745-0

William R Short, Elizabeth D Lowenthal, Florence Momplaisir, Kathleen M Powis, Rachel K Scott, Lynn M Yee, Emily S Miller, Lynne M Mofenson

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引用次数: 0

Abstract

Purpose of review: The objective of this review is to examine the intersection of pregnancy and HIV, focusing on birthing person and fetal health outcomes, prevention of perinatal HIV transmission, and the latest advancements in treatment and care in the United States. It highlights current guidelines, challenges in management, and future directions for improving outcomes.

Recent findings: HIV treatment guidelines continue to highlight key principles for the choice of antiretroviral therapy in pregnancy, challenges, and strategies for adherence support. Guidelines have been updated to reflect patient-centered counseling to support shared decision making about infant feeding. Counseling should begin prior to pregnancy, and be reviewed throughout pregnancy, again at delivery, and throughout the periods when breast/chestfeeding occurs. ART use during pregnancy has significantly reduced perinatal HIV transmission. Ongoing research and collaboration are vital to addressing remaining challenges. Prioritizing maternal and infant health ensures that ART not only prevents transmission but also improves future health for families affected by HIV.

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艾滋病毒和妊娠：导航复杂决策和预防围产期传播。

综述目的：本综述的目的是研究妊娠与HIV的交叉关系，重点关注美国分娩者和胎儿健康结局、围产期HIV传播的预防以及治疗和护理的最新进展。它强调了当前的指导方针、管理方面的挑战以及改善结果的未来方向。最新发现：艾滋病毒治疗指南继续强调妊娠期选择抗逆转录病毒治疗的关键原则、挑战和依从性支持策略。指南已更新，以反映以患者为中心的咨询，以支持关于婴儿喂养的共同决策。咨询应在怀孕前开始，并在整个怀孕期间、分娩时和母乳喂养期间进行复查。怀孕期间使用抗逆转录病毒治疗可显著减少围产期艾滋病毒传播。正在进行的研究和合作对于解决仍然存在的挑战至关重要。优先考虑母婴健康，确保抗逆转录病毒疗法不仅可以预防传播，还可以改善受艾滋病毒影响家庭未来的健康。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current HIV/AIDS Reports INFECTIOUS DISEASES-

CiteScore

8.10

自引率

2.20%

发文量

期刊介绍： This journal intends to provide clear, insightful, balanced contributions by international experts that review the most important, recently published clinical findings related to the diagnosis, treatment, management, and prevention of HIV/AIDS. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as antiretroviral therapies, behavioral aspects of management, and metabolic complications and comorbidity. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. An international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research. Commentaries from well-known figures in the field are also provided.