A Scoring System for Predicting the Cure Rate of Unilateral Idiopathic Sudden Sensorineural Hearing Loss

IF 1.5 4区医学 Q2 OTORHINOLARYNGOLOGY

Clinical Otolaryngology Pub Date : 2025-06-07 DOI:10.1111/coa.14340

Tongxiang Diao, Yixu Wang, Junbo Zhang, Shiming Yang, Xin Ma, Lisheng Yu

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引用次数: 0

Abstract

Background

Due to the clinical heterogeneity of unilateral idiopathic sudden sensorineural hearing loss, its prognosis is difficult to predict. This study aims to establish a system that could incorporate multiple factors for better prediction of the prognosis.

Methods

Seven hundred eighty-four adult patients with unilateral idiopathic sudden sensorineural hearing loss who were hospitalised for treatment between Jan 2016 and Dec 2020 were included. Pure tone audiometry hearing threshold calculated by the average value of hearing thresholds at 250, 500, 1000, 2000, 4000 and 8000 Hz was used for evaluating treatment efficacy.

Results

The final cure rate was 31.0% (232/748). Age, onset-therapy time, initial hearing level, audiogram shape, and vertigo were found to be independently predictive for the prognosis. A scoring system that could incorporate all these five factors based on their prediction weights was then successfully created. The equation of total score was as follows: Total score = 1.2 × Age (score) + 1.6 × Onset-therapy time (score) + 1.3 × Initial hearing level (score) + 2.3 × Audiogram shape (score) + 2.8 × Vertigo (score). The cure rate of patients with scores of < 5 could reach as high as 81.4%, whereas it was only 10.1% in patients with scores of ≥ 12.

Conclusions

This study created a scoring system for predicting the prognosis of unilateral idiopathic sudden sensorineural hearing loss. The cure rates decreased with the increase of score. Patients could be given more individualised treatment according to the preliminary prediction of our system.

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预测单侧特发性突发性感音神经性听力损失治愈率的评分系统。

背景：由于单侧特发性突发性感音神经性听力损失的临床异质性，其预后难以预测。本研究旨在建立一个综合多因素的预后预测系统。方法：选取2016年1月至2020年12月住院治疗的784例单侧特发性突发性感音神经性听力损失成年患者。纯音测听听阈采用250、500、1000、2000、4000、8000 Hz的听阈平均值计算的纯音听阈评价治疗效果。结果：最终治愈率为31.0%（232/748）。发现年龄、起病治疗时间、初始听力水平、听图形状和眩晕是预测预后的独立因素。然后成功创建了一个评分系统，该系统可以根据预测权重将所有这五个因素结合起来。总分公式为：总分= 1.2 ×年龄（分）+ 1.6 ×起病治疗时间（分）+ 1.3 ×初始听力水平（分）+ 2.3 ×听音形态（分）+ 2.8 ×眩晕（分）。结论：本研究建立了预测单侧特发性突发性感音神经性听力损失预后的评分系统。治愈率随评分的增加而降低。根据我们的系统的初步预测，患者可以给予更个性化的治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Otolaryngology 医学-耳鼻喉科学

CiteScore

4.00

自引率

4.80%

发文量

106

审稿时长

>12 weeks

期刊介绍： Clinical Otolaryngology is a bimonthly journal devoted to clinically-oriented research papers of the highest scientific standards dealing with: current otorhinolaryngological practice audiology, otology, balance, rhinology, larynx, voice and paediatric ORL head and neck oncology head and neck plastic and reconstructive surgery continuing medical education and ORL training The emphasis is on high quality new work in the clinical field and on fresh, original research. Each issue begins with an editorial expressing the personal opinions of an individual with a particular knowledge of a chosen subject. The main body of each issue is then devoted to original papers carrying important results for those working in the field. In addition, topical review articles are published discussing a particular subject in depth, including not only the opinions of the author but also any controversies surrounding the subject. • Negative/null results In order for research to advance, negative results, which often make a valuable contribution to the field, should be published. However, articles containing negative or null results are frequently not considered for publication or rejected by journals. We welcome papers of this kind, where appropriate and valid power calculations are included that give confidence that a negative result can be relied upon.