Experimental proof of concept of Positron Annihilation Interaction-Transmission Imaging (PAITI) system

IF 2.8 3区物理与天体物理 Q3 CHEMISTRY, PHYSICAL

Radiation Physics and Chemistry Pub Date : 2025-06-06 DOI:10.1016/j.radphyschem.2025.113041

Rasool Safari , Reza Faghihi , Mohammadreza Parishan , Zahra Rakeb

{"title":"Experimental proof of concept of Positron Annihilation Interaction-Transmission Imaging (PAITI) system","authors":"Rasool Safari , Reza Faghihi , Mohammadreza Parishan , Zahra Rakeb","doi":"10.1016/j.radphyschem.2025.113041","DOIUrl":null,"url":null,"abstract":"<div><div>A novel low-dose multi-parameter imaging system, Positron Annihilation Interaction-Transmission Imaging (PAITI), has recently been introduced through theoretical analysis and simulation studies. PAITI not only provides efficiency maps of the detectors but also extracts about ten 2D maps of the investigated medium. Noteworthy among these maps are absolute representations of the number of accrued interactions, deposited energy, attenuation coefficient, and electron density.</div><div>In this study, we conducted a simple yet robust experimental proof of concept for PAITI, utilizing two single-pixel scintillation detectors, two single-channel analyzers, a delay amplifier, and a coincidence-anticoincidence circuit. Plexiglass, Aluminium, and Iron were chosen as representative mediums. The average percentage errors for determining detector efficiencies, accrued interactions, deposited energies, attenuation values, and electron densities were 5.7 %, 4.4 %, 3.9 %, 5.8 %, and 6.9 %, respectively.</div><div>This experimental validation underscores the potential of an advanced form of PAITI for future applications in diverse fields, such as medical imaging, ion-range prediction in ion therapy, and bone densitometry.</div></div>","PeriodicalId":20861,"journal":{"name":"Radiation Physics and Chemistry","volume":"237 ","pages":"Article 113041"},"PeriodicalIF":2.8000,"publicationDate":"2025-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Radiation Physics and Chemistry","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0969806X2500533X","RegionNum":3,"RegionCategory":"物理与天体物理","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, PHYSICAL","Score":null,"Total":0}

引用次数: 0

Abstract

A novel low-dose multi-parameter imaging system, Positron Annihilation Interaction-Transmission Imaging (PAITI), has recently been introduced through theoretical analysis and simulation studies. PAITI not only provides efficiency maps of the detectors but also extracts about ten 2D maps of the investigated medium. Noteworthy among these maps are absolute representations of the number of accrued interactions, deposited energy, attenuation coefficient, and electron density.

In this study, we conducted a simple yet robust experimental proof of concept for PAITI, utilizing two single-pixel scintillation detectors, two single-channel analyzers, a delay amplifier, and a coincidence-anticoincidence circuit. Plexiglass, Aluminium, and Iron were chosen as representative mediums. The average percentage errors for determining detector efficiencies, accrued interactions, deposited energies, attenuation values, and electron densities were 5.7 %, 4.4 %, 3.9 %, 5.8 %, and 6.9 %, respectively.

This experimental validation underscores the potential of an advanced form of PAITI for future applications in diverse fields, such as medical imaging, ion-range prediction in ion therapy, and bone densitometry.

查看原文本刊更多论文

正电子湮灭相互作用-透射成像系统概念的实验证明

通过理论分析和仿真研究，提出了一种新型的低剂量多参数成像系统——正电子湮灭相互作用-透射成像（PAITI）。PAITI不仅提供了探测器的效率图，而且还提取了大约10个所研究介质的二维图。这些图中值得注意的是累积相互作用、沉积能量、衰减系数和电子密度的绝对表示。在这项研究中，我们使用两个单像素闪烁探测器，两个单通道分析仪，一个延迟放大器和一个符合-反符合电路，对PAITI进行了简单而强大的概念实验证明。选择有机玻璃、铝和铁作为代表性介质。测定探测器效率、累积相互作用、沉积能量、衰减值和电子密度的平均误差百分比分别为5.7%、4.4%、3.9%、5.8%和6.9%。这项实验验证强调了一种先进形式的PAITI在未来不同领域的应用潜力，如医学成像、离子治疗中的离子范围预测和骨密度测定。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Radiation Physics and Chemistry 化学-核科学技术

CiteScore

5.60

自引率

17.20%

发文量

574

审稿时长

12 weeks

期刊介绍： Radiation Physics and Chemistry is a multidisciplinary journal that provides a medium for publication of substantial and original papers, reviews, and short communications which focus on research and developments involving ionizing radiation in radiation physics, radiation chemistry and radiation processing. The journal aims to publish papers with significance to an international audience, containing substantial novelty and scientific impact. The Editors reserve the rights to reject, with or without external review, papers that do not meet these criteria. This could include papers that are very similar to previous publications, only with changed target substrates, employed materials, analyzed sites and experimental methods, report results without presenting new insights and/or hypothesis testing, or do not focus on the radiation effects.