Borderline acceleration in blood epigenetic age of unclear biological importance in knee OA progression: Specimens and data from the Osteoarthritis Initiative and Johnston County Osteoarthritis Project

Abstract

Aging is among the strongest risk factors for osteoarthritis (OA). Although epigenetics plays a role in OA, previous studies have not found accelerated peripheral blood epigenetic aging among OA patients overall. The goal of this study was to evaluate peripheral blood epigenetic aging rates among various types of OA progressors and non-progressors (NPs).