Magnitude of ectopic pregnancy, management methods, and its associated factors among pregnant women attending Ambo University Referral Hospital in Oromia Regional State, Ethiopia: A seven years retrospective institutional based cross-sectional study.

PLOS global public health Pub Date : 2025-06-05 eCollection Date: 2025-01-01 DOI:10.1371/journal.pgph.0004611
Nigussie Tesfaye Gizaw, Mekbeb Afework K/Mariam, Motuma Gutu Fayera
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Abstract

Background: Ectopic pregnancy is the implantation of a blastocyst outside of the endometrial lining of the uterus. Ectopic pregnancy can take several forms, including ovarian, abdominal, and tubal. The most prevalent place for ectopic pregnancy is the fallopian tube, which accounts for over 97.7% of all ectopic gestations. The ampulla accounts for around 80% of tubal pregnancy, followed by the isthmus (12%), fimbria (5%). Ectopic pregnancy is diagnosed with the classic triad of amenorrhea, abdominal pain, vaginal bleeding, and a positive pregnancy test.

Objective: This study aimed to assess the magnitude of ectopic pregnancy, its management outcome, and associated factors among pregnant women attending Ambo University Referral Hospital in the Oromia Region, Ethiopia, in 2024.

Methods: A seven-year retrospective cross-sectional study, from February 2018 to April 2024, was conducted at the Ambo University Referral Hospital, which is located in Ambo town, Ethiopia. Data concerning all pregnant mothers who were admitted and managed for ectopic pregnancy were extracted from the medical records of patients and the operation book by a trained data collector through Kobo Toolbox electronic data collection software. The collected data was checked first for its completeness, and it was exported into SPSS version 26 software for data analysis. Then Descriptive statistics were employed for summarizing the data, and bivariate and multivariate logistic regression analyses were used to identify the independent effect of the predictor variable on the outcome variable.

Results: From February 2018 to April 2024, there were 17,687 total pregnancies, 6,249 gynecologic admissions, and 182 cases of ectopic pregnancies at Ambo University Referral Hospital. A total of 173 patients with ectopic pregnancy were included in the data analysis. The magnitude of ectopic pregnancy was 0.98% among the total pregnancies and accounted for 2.77% of all gynecological admissions during the study period. Most of the patients, 81 (46.8%), were in the 25-29 years age group, with a mean age of 27.16 ± SD 4.77 years. Mothers who had a previous history of abortion, a history of pelvic inflammatory disease, a history of ectopic pregnancy, or a history of tubal surgery had a statistically significant association with ectopic pregnancy. The majority of the patients were married, 98 (56.6%), and urban residents, 121 (69.9%). The majority of ectopic pregnancies occurred on the right side of the fallopian tube 144 (83.24%). Among the majority of ectopic pregnancies, 159 (61.3%) were tubal ampullary ectopic pregnancies.

Conclusion and recommendation: The major risk factors identified in this study were previous abortion, pelvic inflammatory disease, a previous history of ectopic pregnancy, and previous tubal surgery. The magnitude of the ectopic pregnancy in this study was 0.98%, which is similar to the global range. The majority of ectopic pregnancies occurred on the right side of the fallopian tube 144 (83.24%) and 160 (92.49%) were ruptured. Further research is needed to assess why ectopic pregnancy is most common in the right fallopian tube.

埃塞俄比亚奥罗米亚地区州安博大学转诊医院孕妇的异位妊娠程度、管理方法及其相关因素:一项基于机构的7年回顾性横断面研究。
背景:异位妊娠是指在子宫内膜外植入囊胚。异位妊娠有多种形式,包括卵巢、腹腔和输卵管。输卵管是宫外孕最常见的部位,占所有宫外孕的97.7%以上。壶腹约占输卵管妊娠的80%,其次是峡部(12%),菌膜(5%)。异位妊娠的诊断是闭经、腹痛、阴道出血和妊娠试验阳性的典型三联征。目的:本研究旨在评估2024年在埃塞俄比亚奥罗米亚地区安博大学转诊医院就诊的孕妇异位妊娠的程度、处理结果和相关因素。方法:2018年2月至2024年4月,在位于埃塞俄比亚安博镇的安博大学转诊医院进行了一项为期7年的回顾性横断面研究。由训练有素的数据采集人员通过Kobo Toolbox电子数据采集软件从患者病历和手术手册中提取所有因异位妊娠入院和处理的孕妇的数据。首先对收集到的数据进行完整性检查,并导出到SPSS 26版软件中进行数据分析。然后采用描述性统计对数据进行汇总,并采用双变量和多变量logistic回归分析确定预测变量对结局变量的独立影响。结果:2018年2月至2024年4月,安博大学转诊医院共发生妊娠17687例,妇科住院6249例,异位妊娠182例。数据分析共纳入173例异位妊娠患者。异位妊娠发生率占总妊娠的0.98%,占研究期间所有妇科入院人数的2.77%。81例(46.8%)患者年龄在25 ~ 29岁,平均年龄27.16±SD 4.77岁。有流产史、盆腔炎史、异位妊娠史或输卵管手术史的母亲与异位妊娠有统计学显著相关。以已婚98例(56.6%)、城镇居民121例(69.9%)为主。异位妊娠多发生在输卵管右侧144(83.24%)。宫外孕多数为输卵管壶腹宫外孕159例(61.3%)。结论和建议:本研究确定的主要危险因素是既往流产、盆腔炎、既往异位妊娠史和既往输卵管手术。本研究异位妊娠的发生率为0.98%,与全球范围相似。多数异位妊娠发生在右侧输卵管,破裂144例(83.24%),破裂160例(92.49%)。需要进一步的研究来评估为什么异位妊娠最常见于右输卵管。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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