Vernal Keratoconjunctivitis: Impact on Children.

IF 2.1 4区 医学 Q2 OPHTHALMOLOGY
Sophie Z Gu, Danielle Trief
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引用次数: 0

Abstract

Abstract: Vernal keratoconjunctivitis (VKC) is a seasonally recurring form of allergic conjunctivitis that leads to bilateral inflammation of the cornea and conjunctiva. Symptoms may include itching, foreign body sensation, discharge, and conjunctival hyperemia. Severe cases may result in corneal complications including erosions, shield ulcers, plaques, microbial keratitis, corneal scarring, limbal stem cell deficiency, and keratoconus. Epidemiological data reveal that it mainly affects children and young adults, with male predominance and a higher prevalence in warmer climates. The etiology is multifactorial, involving triggers from environmental allergens. Both type I and type IV hypersensitivity reactions have been implicated. Vernal keratoconjunctivitis may significantly impact visual acuity and quality of life, especially in school-aged children. Management strategies include allergen avoidance, topical treatments, and immunomodulators. Despite therapeutic advances, VKC remains a significant cause of morbidity, highlighting the need for prompt diagnosis and treatment to mitigate long-term impacts on vision and quality of life.

春季角膜结膜炎:对儿童的影响。
摘要:春性角膜结膜炎(VKC)是一种季节性复发的变应性结膜炎,可导致双侧角膜和结膜炎症。症状可能包括瘙痒、异物感、分泌物和结膜充血。严重者可导致角膜并发症,包括糜烂、盾性溃疡、斑块、微生物性角膜炎、角膜瘢痕、角膜缘干细胞缺乏和圆锥角膜。流行病学数据显示,该病主要影响儿童和青壮年,以男性为主,在气候较暖的地区发病率较高。病因是多因素的,包括环境过敏原的触发。I型和IV型超敏反应都有牵连。春性角膜结膜炎可显著影响视力和生活质量,尤其是学龄儿童。管理策略包括避免过敏原、局部治疗和免疫调节剂。尽管治疗取得了进展,但VKC仍然是发病率的重要原因,因此需要及时诊断和治疗,以减轻对视力和生活质量的长期影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
4.50
自引率
4.30%
发文量
150
审稿时长
6-12 weeks
期刊介绍: Eye & Contact Lens: Science and Clinical Practice is the official journal of the Contact Lens Association of Ophthalmologists (CLAO), an international educational association for anterior segment research and clinical practice of interest to ophthalmologists, optometrists, and other vision care providers and researchers. Focusing especially on contact lenses, it also covers dry eye disease, MGD, infections, toxicity of drops and contact lens care solutions, topography, cornea surgery and post-operative care, optics, refractive surgery and corneal stability (eg, UV cross-linking). Peer-reviewed and published six times annually, it is a highly respected scientific journal in its field.
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