Evaluation of visual evoked potentials in patients with Hashimoto thyroiditis.

IF 0.9 4区医学 Q4 CLINICAL NEUROLOGY

Ideggyogyaszati Szemle-Clinical Neuroscience Pub Date : 2025-05-30 DOI:10.18071/isz.78.0181

Pinar Bengi Boz, Muhammet Ates, Murat Boz

{"title":"Evaluation of visual evoked potentials in patients with Hashimoto thyroiditis.","authors":"Pinar Bengi Boz, Muhammet Ates, Murat Boz","doi":"10.18071/isz.78.0181","DOIUrl":null,"url":null,"abstract":"Background and purpose: Our aim was to use visual evoked potentials (VEP) to evaluate changes in brain bioelectrical activity in Hashimoto thyroiditis patients with normal neurological examination and imaging findings and to correlate the evoked potential parameters with clinical data.Methods: Our aim was to use visual evoked potentials (VEP) to evaluate changes in brain bioelectrical activity in Hashimoto thyroiditis patients with normal neurological examination and imaging findings and to correlate the evoked potential parameters with clinical data.Results: Of the Hashimoto thyroiditis patients included in the study, 92% (n=69) were female, the mean age was 40.3±12.2 years, and the mean disease duration was 5.7±7.5 years (range: 0-40 years, median: 4 years). Euthyroid patients showed significantly longer P100 latency difference and higher N75/P100 amplitude than the control group (p=0.014 and 0.007, respectively). Elevated thyroid-stimulating hormone level was associated with longer N75 and P100 latencies.Conclusion: Our results demonstrated the presence of abnormal brain bioelectric activity in Hashimoto thyroiditis patients without active neurological findings. These effects increase with disease severity and duration and necessitate the development of early treatment strategies to halt the progressive autoimmune process.","PeriodicalId":50394,"journal":{"name":"Ideggyogyaszati Szemle-Clinical Neuroscience","volume":"78 5-6","pages":"181-188"},"PeriodicalIF":0.9000,"publicationDate":"2025-05-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Ideggyogyaszati Szemle-Clinical Neuroscience","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.18071/isz.78.0181","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CLINICAL NEUROLOGY","Score":null,"Total":0}

引用次数: 0

Abstract

Background and purpose: Our aim was to use visual evoked potentials (VEP) to evaluate changes in brain bioelectrical activity in Hashimoto thyroiditis patients with normal neurological examination and imaging findings and to correlate the evoked potential parameters with clinical data.

Methods: Our aim was to use visual evoked potentials (VEP) to evaluate changes in brain bioelectrical activity in Hashimoto thyroiditis patients with normal neurological examination and imaging findings and to correlate the evoked potential parameters with clinical data.

Results: Of the Hashimoto thyroiditis patients included in the study, 92% (n=69) were female, the mean age was 40.3±12.2 years, and the mean disease duration was 5.7±7.5 years (range: 0-40 years, median: 4 years). Euthyroid patients showed significantly longer P100 latency difference and higher N75/P100 amplitude than the control group (p=0.014 and 0.007, respectively). Elevated thyroid-stimulating hormone level was associated with longer N75 and P100 latencies.

Conclusion: Our results demonstrated the presence of abnormal brain bioelectric activity in Hashimoto thyroiditis patients without active neurological findings. These effects increase with disease severity and duration and necessitate the development of early treatment strategies to halt the progressive autoimmune process.

查看原文本刊更多论文

桥本甲状腺炎患者的视觉诱发电位评价。

背景和目的：我们的目的是使用视觉诱发电位（VEP）来评估神经系统检查和影像学检查正常的桥本甲状腺炎患者脑生物电活动的变化，并将诱发电位参数与临床数据联系起来。方法：我们的目的是利用视觉诱发电位（VEP）来评估神经系统检查和影像学检查正常的桥本甲状腺炎患者脑生物电活动的变化，并将诱发电位参数与临床数据相关联。结果：纳入研究的桥本甲状腺炎患者中，92% （n=69）为女性，平均年龄为40.3±12.2岁，平均病程为5.7±7.5年（范围：0-40年，中位数：4年）。甲状腺功能正常患者的P100潜伏期差异明显大于对照组（p=0.014, p= 0.007）， N75/P100振幅显著高于对照组（p=0.014, p= 0.007）。促甲状腺激素水平升高与N75和P100潜伏期延长有关。结论：我们的研究结果表明桥本甲状腺炎患者存在异常的脑生物电活动，但没有活跃的神经学表现。这些影响随着疾病的严重程度和持续时间的增加而增加，因此需要制定早期治疗策略来阻止自身免疫过程的进展。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Ideggyogyaszati Szemle-Clinical Neuroscience CLINICAL NEUROLOGY-NEUROSCIENCES

CiteScore

1.30

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： The aim of Clinical Neuroscience (Ideggyógyászati Szemle) is to provide a forum for the exchange of clinical and scientific information for a multidisciplinary community. The Clinical Neuroscience will be of primary interest to neurologists, neurosurgeons, psychiatrist and clinical specialized psycholigists, neuroradiologists and clinical neurophysiologists, but original works in basic or computer science, epidemiology, pharmacology, etc., relating to the clinical practice with involvement of the central nervous system are also welcome.