A microglia identity crisis.

IF 15 1区医学 Q1 NEUROSCIENCES

Neuron Pub Date : 2025-06-04 DOI:10.1016/j.neuron.2025.05.008

Jessie Axsom, F Chris Bennett

引用次数: 0

Abstract

What makes a microglia a microglia? In a recent issue of Cell, Wu et al.¹ discover immune cells with microglial gene expression, epigenetic profiles, and ontogeny in the peripheral nervous system of large vertebrates, calling into question long-standing assumptions about microglia identity.

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小胶质细胞身份危机。

是什么使小胶质细胞成为小胶质细胞？在最近一期的《细胞》杂志上，Wu等人1发现了大型脊椎动物周围神经系统中具有小胶质细胞基因表达、表观遗传特征和个体发育的免疫细胞，这对长期以来关于小胶质细胞身份的假设提出了质疑。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Neuron 医学-神经科学

CiteScore

24.50

自引率

3.10%

发文量

382

审稿时长

1 months

期刊介绍： Established as a highly influential journal in neuroscience, Neuron is widely relied upon in the field. The editors adopt interdisciplinary strategies, integrating biophysical, cellular, developmental, and molecular approaches alongside a systems approach to sensory, motor, and higher-order cognitive functions. Serving as a premier intellectual forum, Neuron holds a prominent position in the entire neuroscience community.