Quantitative tractography: joys and sorrows.

IF 2.7 3区医学 Q1 ANATOMY & MORPHOLOGY

Brain Structure & Function Pub Date : 2025-06-06 DOI:10.1007/s00429-025-02939-z

Alessandro Daducci, Simona Schiavi

引用次数: 0

Abstract

Quantitative tractography is the term used to indicate informing the estimation of the major axonal pathways of the brain from diffusion MRI with microstructural information (such as volume, myelin, axonal densities, etc.) to deliver veridical and biologically meaningful connectomes. The literature is replete with studies showing promising results obtained with such methods; however, did you know that these methods also have some subtle pitfalls that aren't immediately apparent but, if neglected, could result in incorrect or biased conclusions? This brief paper provides an overview of such pitfalls and solutions to mitigate them.

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定量气管造影：喜怒哀乐。

定量神经束造影（Quantitative tractography）是指通过弥散性磁共振成像（diffusion MRI）对大脑主要轴突通路的微观结构信息（如体积、髓鞘、轴突密度等）进行估计，从而提供真实的、具有生物学意义的连接体。文献中充满了用这种方法获得有希望的结果的研究；然而，你知道这些方法也有一些不易察觉的陷阱，但如果忽视，可能会导致不正确或有偏见的结论吗？这篇简短的文章概述了这些陷阱和减轻它们的解决方案。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Brain Structure & Function 医学-解剖学与形态学

CiteScore

6.00

自引率

6.50%

发文量

168

审稿时长

8 months

期刊介绍： Brain Structure & Function publishes research that provides insight into brain structure−function relationships. Studies published here integrate data spanning from molecular, cellular, developmental, and systems architecture to the neuroanatomy of behavior and cognitive functions. Manuscripts with focus on the spinal cord or the peripheral nervous system are not accepted for publication. Manuscripts with focus on diseases, animal models of diseases, or disease-related mechanisms are only considered for publication, if the findings provide novel insight into the organization and mechanisms of normal brain structure and function.