Molecular Evidence for Greater Diversity Within Acanthamoeba.

IF 1.2 3区农林科学 Q4 PARASITOLOGY

Acta Parasitologica Pub Date : 2025-06-06 DOI:10.1007/s11686-025-01068-1

Daniele Corsaro

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引用次数: 0

Abstract

Purpose: The opportunistic parasite Acanthamoeba comprises several genotypes. However, partial rDNA sequences and previous work suggest the possible existence of other, as yet unrecorded lineages. This study aims to identify such sequences and clarify their relationships.

Methods: In this study, a broad search for possible new rDNA sequences belonging to Acanthamoeba and its closest relatives was conducted by exploring available data in GenBank.

Results: Several partial sequences, including 18S and/or LSU rDNA sequences, were identified, representing additional genotypes within the Acanthamoeba culbertsoni and Acanthamoeba micheli groups, as well as entirely new near-basal lineages for which no morphological data are available. Furthermore, some sequences could belong to new species of Protacanthamoeba, Luapeleamoeba, and/or a close relative within Acanthamoebidae.

Conclusion: The study identified several highly divergent partial 18 S/LSU rDNA sequences that branch consistently in phylogenetic trees and likely represent new lineages. Given the increasing diversity of Acanthamoeba and its close relatives, further efforts to isolate these strains for morphological study are recommended.

查看原文本刊更多论文

棘阿米巴原虫内部更大多样性的分子证据。

目的：棘阿米巴机会性寄生虫包括多种基因型。然而，部分rDNA序列和先前的工作表明，可能存在其他尚未记录的谱系。本研究旨在确定这些序列并澄清它们之间的关系。方法：本研究利用GenBank的现有数据，对棘阿米巴及其近亲可能的新rDNA序列进行了广泛的搜索。结果：鉴定了包括18S和/或LSU rDNA序列在内的几个部分序列，代表了culbertsoni棘阿米巴和micheli棘阿米巴类群中的其他基因型，以及没有形态学数据的全新近基谱系。此外，一些序列可能属于原棘阿米巴新种、Luapeleamoeba和/或棘阿米巴科的近缘种。结论：该研究确定了几个高度分化的部分18s /LSU rDNA序列，这些序列在系统发育树中分支一致，可能代表新的谱系。鉴于棘阿米巴及其近亲的多样性日益增加，建议进一步分离这些菌株进行形态学研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Acta Parasitologica 医学-寄生虫学

CiteScore

3.10

自引率

6.70%

发文量

149

审稿时长

6-12 weeks

期刊介绍： Acta Parasitologica is an international journal covering the latest advances in the subject. Acta Parasitologica publishes original papers on all aspects of parasitology and host-parasite relationships, including the latest discoveries in biochemical and molecular biology of parasites, their physiology, morphology, taxonomy and ecology, as well as original research papers on immunology, pathology, and epidemiology of parasitic diseases in the context of medical, veterinary and biological sciences. The journal also publishes short research notes, invited review articles, book reviews. The journal was founded in 1953 as "Acta Parasitologica Polonica" by the Polish Parasitological Society and since 1954 has been published by W. Stefanski Institute of Parasitology of the Polish Academy of Sciences in Warsaw. Since 1992 in has appeared as Acta Parasitologica in four issues per year.