Development and validation of a predictive scoring system for excessive intraoperative blood loss in orthognathic surgery.

B Kampeera, N Sriyaranya, Y Aschaitrakool, W Powcharoen
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Abstract

Risk stratification for excessive bleeding prior to orthognathic surgery is necessary for optimizing patient safety and enhancing postoperative recovery. The aim of this study was to develop and validate a simplified scoring system for predicting excessive intraoperative blood loss (IBL) during orthognathic surgery. This retrospective cohort study included 361 patients who underwent orthognathic surgery. Factors related to excessive IBL were analysed. The candidate predictors for excessive IBL were determined by logistic regression analysis. The performance of the model was assessed through its discrimination ability and a calibration plot. Internal validation was done by bootstrap resampling technique. The regression coefficients were transformed into a scoring system. Excessive IBL occurred in 32.7% of patients (118/361). The predictive scoring system included three predictors: body mass index (score 0, 1.5, 2: overweight, normal weight, underweight), systolic blood pressure (score 0, 1: <130, ≥130 mmHg), and operative time (score 0, 2.5: ≤4, >4 h). The area under the receiver operating characteristic curve (AUROC) for discrimination ability was 0.828 (internal validation: C-statistic 0.812). Risk was then classified as low (0-2.5 points) or high (3-5.5 points). The prognostic ability of this simplified scoring system was found to be clinically acceptable for predicting excessive IBL during orthognathic surgery.

正颌手术术中失血过多的预测评分系统的开发和验证。
正颌手术前出血风险分层是优化患者安全性和增强术后恢复的必要条件。本研究的目的是开发和验证一种简化的评分系统,用于预测正颌手术中过多的术中出血量(IBL)。这项回顾性队列研究包括361例接受正颌手术的患者。分析与IBL过度相关的因素。通过逻辑回归分析确定过度IBL的候选预测因子。通过模型的识别能力和标定图对模型的性能进行了评价。内部验证采用自举重采样技术。将回归系数转化为评分系统。32.7%的患者出现过度IBL(118/361)。预测评分系统包括三个预测指标:体重指数(评分0,1.5,2:超重,正常体重,体重不足),收缩压(评分0,1:4 h)。鉴别能力的受试者工作特征曲线下面积(AUROC)为0.828(内部验证:c统计量0.812)。然后将风险分为低(0-2.5分)和高(3-5.5分)。该简化评分系统的预后能力在临床上可用于预测正颌手术期间过度IBL。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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