Formulation of Tooth Mousse Containing Grape Seed Extract and Comparative Evaluation of Its Remineralizing Effect with GC Tooth Mousse: An In Vitro Study.

Abstract

Background: Dental caries is one of the most prevalent chronic infectious diseases, with its incidence increasing significantly over time. The global prevalence rate of dental caries in primary teeth stands at approximately 46.2% (Furiga et al.). To combat this widespread issue, remineralizing agents play a crucial role in reducing the prevalence rate, helping to restore and strengthen the demineralized tooth surface.

Objectives: The aim of this in vitro study is to formulate the grape seed extract (GSE)-containing tooth mousse and to compare the remineralizing property with commercially available GC Tooth Mousse.

Materials and methodology: The remineralizing property of a formulated GSE-containing tooth mousse was compared with the gold standard GC Tooth Mousse by checking the microhardness values in extracted teeth samples divided into two groups: group A, treated with the GSE-containing tooth mousse, and group B, treated with the standardized GC Tooth Mousse.

Results: There was a significant difference in microhardness between the baseline and after remineralization within each group. In the intergroup comparison after remineralization, the microhardness of group A was significantly greater than that of group B.

Conclusion: Both the commercially available GC Tooth Mousse and the formulated GSE-containing tooth mousse demonstrated good remineralizing potential, with the GSE-containing tooth mousse showing slightly better remineralizing potential compared to the commercially available GC Tooth Mousse.

How to cite this article: Gujarathi AM, Shah P, Chaudhary S, et al. Formulation of Tooth Mousse Containing Grape Seed Extract and Comparative Evaluation of Its Remineralizing Effect with GC Tooth Mousse: An In Vitro Study. Int J Clin Pediatr Dent 2025;18(4):412-419.