The Role of Quantitative DMSA Scan Analysis in Assessing Prognosis of Acute Pyelonephritis in Children.

IF 1 4区医学 Q3 PEDIATRICS

Clinical Pediatrics Pub Date : 2025-07-01 Epub Date: 2024-12-31 DOI:10.1177/00099228241307441

Roya Tahlili, Alireza Mardanshahi, Seyed Mohammad Abedi, Hamid Mohammadjafari

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引用次数: 0

Abstract

Objective: We assessed the quantitative pattern of Dimercaptosuccinic acid scan (DMSA) in children with acute pyelonephritis.

Methods: In a retrospective study, we reviewed DMSA of children with APN based on 7 qualitative and quantitative items.

Results: A total of 186 patients (age 27.8 ± 25.9 months, 157 (84%) female) enrolled in the study. The global defect was not found in 90% of children as well differential function ≥40% in 86% of patients. The other 5 items showed abnormal findings in 57% to 67% of children. Abnormality in the extent of defect, total points of involvement, number of involved segments, and differential renal function significantly predict late DMSA disturbances. There was no significant difference between patients with different grades of vesicoureteral reflux in any items on DMSA. We found no significant relationship between any items on DMSA and recurrent urinary tract infection (UTI).

Conclusion: Quantitative assessment of DMSA offers at least 4 items that reveal subtle cortical involvements with long-term significance.

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定量DMSA扫描分析在评估儿童急性肾盂肾炎预后中的作用。

目的：探讨小儿急性肾盂肾炎二巯基琥珀酸扫描（DMSA）的定量模式。方法：采用回顾性研究方法，对APN患儿的DMSA进行定性和定量分析。结果：186例患者（年龄27.8±25.9个月）入组，其中157例（84%）为女性。90%的儿童未发现整体缺陷，86%的患者差异功能≥40%。其余5项有57% ~ 67%的儿童出现异常。缺损程度、总受累点、受累节段数量和肾功能差异的异常可显著预测DMSA的晚期紊乱。不同程度膀胱输尿管反流的患者在DMSA的任何项目上均无显著差异。我们没有发现DMSA的任何项目与复发性尿路感染（UTI）有显著的关系。结论：DMSA定量评估提供了至少4个项目，揭示了具有长期意义的细微皮层受累。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Pediatrics 医学-小儿科

CiteScore

2.10

自引率

6.20%

发文量

189

审稿时长

3-8 weeks

期刊介绍： Clinical Pediatrics (CLP) a peer-reviewed monthly journal, is a must read for the busy pediatrician. CLP contains state-of-the-art, accurate, concise and down-to earth information on practical, everyday child care topics whether they are clinical, scientific, behavioral, educational, or ethical.