Feasibility and Outcomes of Gait Training with a Powered Exoskeleton in Individuals with Multiple Sclerosis.

IF 2.4 4区医学 Q1 REHABILITATION

American Journal of Physical Medicine & Rehabilitation Pub Date : 2025-06-03 DOI:10.1097/PHM.0000000000002772

Samantha J Stallkamp Tidd, Nicolas R Thompson, Susan M Linder, Randy Karim, Francois Bethoux

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引用次数: 0

Abstract

Objective: To report on real-world use of a powered exoskeleton (PES) for outpatient gait training in MS.

Design: Retrospective chart review on 21 patients with MS who completed physical therapy gait training sessions using a PES. Training descriptors, PES parameters, adverse events (AE), and performance on mobility tests without PES were compared between first and last session.

Results: The median number of gait training sessions was 11. There was a statistically significant increase in walk time (p = 0.008), number of steps (p = 0.011), and programmed step length (p < 0.001) while using PES. Three patients exhibited a greater than 20% increase in walking speed on the Timed 25 Foot Walk. The time to complete the Timed Up and Go (TUG) increased (p = 0.029), although patients who did not use a wheelchair outdoors showed a smaller mean increase in TUG time (0.59 s vs. 8.69 s, p = 0.050). Five patients had one mild AE without impact on training participation.

Conclusion: Our findings suggest that gait training with a PES is safe and feasible in individuals with MS. Changes in mobility outcomes without PES were highly variable between patients. Further research is needed to establish the value of PES gait training and predictors of response to gait training.

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用动力外骨骼对多发性硬化症患者进行步态训练的可行性和结果。

目的：报道动力外骨骼（PES）在MS门诊步态训练中的实际应用。设计：对21例使用PES完成物理治疗步态训练的MS患者进行回顾性分析。训练描述、PES参数、不良事件（AE）和在无PES的情况下的活动能力测试中的表现在第一次和最后一次之间进行比较。结果：步态训练的中位数为11次。使用PES时，行走时间（p = 0.008）、步数（p = 0.011）和程序步长（p < 0.001）均有统计学意义上的显著增加。三名患者在25英尺步行时的步行速度增加了20%以上。完成Timed Up and Go （TUG）的时间增加了（p = 0.029），尽管未在户外使用轮椅的患者在TUG时间上的平均增加较小（0.59 s vs. 8.69 s, p = 0.050）。5例患者有1例轻度AE，但不影响训练参与。结论：我们的研究结果表明，在ms患者中，使用PES进行步态训练是安全可行的。需要进一步的研究来确定PES步态训练的价值和步态训练反应的预测因子。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

American Journal of Physical Medicine & Rehabilitation 医学-康复医学

CiteScore

4.60

自引率

6.70%

发文量

423

审稿时长

1 months

期刊介绍： American Journal of Physical Medicine & Rehabilitation focuses on the practice, research and educational aspects of physical medicine and rehabilitation. Monthly issues keep physiatrists up-to-date on the optimal functional restoration of patients with disabilities, physical treatment of neuromuscular impairments, the development of new rehabilitative technologies, and the use of electrodiagnostic studies. The Journal publishes cutting-edge basic and clinical research, clinical case reports and in-depth topical reviews of interest to rehabilitation professionals. Topics include prevention, diagnosis, treatment, and rehabilitation of musculoskeletal conditions, brain injury, spinal cord injury, cardiopulmonary disease, trauma, acute and chronic pain, amputation, prosthetics and orthotics, mobility, gait, and pediatrics as well as areas related to education and administration. Other important areas of interest include cancer rehabilitation, aging, and exercise. The Journal has recently published a series of articles on the topic of outcomes research. This well-established journal is the official scholarly publication of the Association of Academic Physiatrists (AAP).