{"title":"Electrochemical sensing of pharmaceutical pollutants using modified glassy carbon electrodes with nanostructures: A review","authors":"Emmanuel Kipkorir, Otieno Kimani","doi":"10.1016/j.inoche.2025.114827","DOIUrl":null,"url":null,"abstract":"<div><div>Pharmaceutical pollutants pose a significant threat to environmental and human health due to their persistence and bioaccumulation. Electrochemical sensing has emerged as a powerful technique for detecting these contaminants with high sensitivity, selectivity, and rapid response times. Among various electrode materials, modified glassy carbon electrodes (GCEs) incorporating nanostructures have gained considerable attention for their enhanced electrochemical performance. This review provides a comprehensive overview of recent advancements in the electrochemical sensing of pharmaceutical pollutants using nanostructure-modified GCEs. We discuss different types of nanomaterials, including metal nanoparticles, carbon-based nanostructures, and metal–organic frameworks, highlighting their roles in improving electron transfer, surface area, and analyte interaction. Furthermore, we explore the analytical performance of these sensors, challenges in their practical application, and future perspectives on the development of highly efficient electrochemical platforms for pharmaceutical pollutant detection.</div></div>","PeriodicalId":13609,"journal":{"name":"Inorganic Chemistry Communications","volume":"179 ","pages":"Article 114827"},"PeriodicalIF":4.4000,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Inorganic Chemistry Communications","FirstCategoryId":"92","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S138770032500944X","RegionNum":3,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, INORGANIC & NUCLEAR","Score":null,"Total":0}
引用次数: 0
Abstract
Pharmaceutical pollutants pose a significant threat to environmental and human health due to their persistence and bioaccumulation. Electrochemical sensing has emerged as a powerful technique for detecting these contaminants with high sensitivity, selectivity, and rapid response times. Among various electrode materials, modified glassy carbon electrodes (GCEs) incorporating nanostructures have gained considerable attention for their enhanced electrochemical performance. This review provides a comprehensive overview of recent advancements in the electrochemical sensing of pharmaceutical pollutants using nanostructure-modified GCEs. We discuss different types of nanomaterials, including metal nanoparticles, carbon-based nanostructures, and metal–organic frameworks, highlighting their roles in improving electron transfer, surface area, and analyte interaction. Furthermore, we explore the analytical performance of these sensors, challenges in their practical application, and future perspectives on the development of highly efficient electrochemical platforms for pharmaceutical pollutant detection.
期刊介绍:
Launched in January 1998, Inorganic Chemistry Communications is an international journal dedicated to the rapid publication of short communications in the major areas of inorganic, organometallic and supramolecular chemistry. Topics include synthetic and reaction chemistry, kinetics and mechanisms of reactions, bioinorganic chemistry, photochemistry and the use of metal and organometallic compounds in stoichiometric and catalytic synthesis or organic compounds.