Influence of mood disorders on outcomes of polycystic ovarian syndrome - A national inpatient sample study - 2016–2020

IF 2.5 Q3 ENDOCRINOLOGY & METABOLISM
Bob Weng , Reid Morrissey , Jenna Lehn , Mustafa Beidas , Tauseef Abubakar , Mohsin Mirza
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Abstract

Background

Polycystic ovarian syndrome (PCOS) is a dysregulated metabolic disorder causing hyperandrogenism, oligomenorrhea/anovulation, and ovarian cysts. The effects of PCOS extend beyond the reproductive detriments, notably an association with mood disorders. Existing literature is limited but suggests comorbid mood derangements increase the severity of PCOS symptoms and comprise a significant portion of healthcare costs in the U.S. Our study aims to further examine the impact of PCOS on the hospitalization course and costs.

Methods

Using data for females ages 18–50 from the National Inpatient Sample (NIS) between 2016 and 2020, a PCOS group was compared to a non-PCOS group for women hospitalized with mood disorders. Length of stay (LOS), hospital costs, and demographic characteristics were analyzed.

Results

PCOS patients accumulated significantly higher LOS and hospital cost. They also were significantly younger, predominantly Caucasian, covered by private insurance, and earned more income. There was a disproportionate use of Medicare for both groups given the younger sample.

Conclusion

Further investigation of demographic nuances and a multidisciplinary approach to PCOS, including policy changes and patient education starting at a young age, should be taken to better understand disease impact on different communities and address the broad scope of the disease (i.e. psychosocial) to reduce its healthcare burden.
情绪障碍对多囊卵巢综合征结局的影响——2016-2020年全国住院患者样本研究
背景:多囊卵巢综合征(PCOS)是一种代谢失调的疾病,可导致雄激素分泌过多、月经减少/无排卵和卵巢囊肿。多囊卵巢综合征的影响超出了生殖损害,特别是与情绪障碍有关。现有文献有限,但表明共病性情绪障碍增加了多囊卵巢综合征症状的严重程度,并构成了美国医疗保健费用的很大一部分。我们的研究旨在进一步研究多囊卵巢综合征对住院过程和费用的影响。方法利用2016年至2020年全国住院患者样本(NIS)中18-50岁女性的数据,比较PCOS组和非PCOS组住院的情绪障碍女性。分析住院时间(LOS)、住院费用和人口统计学特征。结果spcos患者的LOS和住院费用均显著增高。他们也明显更年轻,主要是高加索人,有私人保险,收入更高。考虑到样本较年轻,这两个群体都不成比例地使用医疗保险。结论应进一步调查多囊卵巢综合征的人口统计学差异,并采取多学科方法,包括政策变化和从年轻开始的患者教育,以更好地了解疾病对不同社区的影响,并解决疾病的广泛范围(即心理社会),以减轻其医疗负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Comprehensive psychoneuroendocrinology
Comprehensive psychoneuroendocrinology Psychiatry and Mental Health
CiteScore
3.10
自引率
0.00%
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审稿时长
62 days
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