{"title":"A Rare Case of Disseminated Varicella Zoster Virus (VZV) Infection Complicated by VZV Pneumonia.","authors":"Suhel A Sabunwala, Tuhina Cornelius","doi":"10.7759/cureus.84630","DOIUrl":null,"url":null,"abstract":"<p><p>Disseminated varicella zoster virus (VZV) infection is rare in older adults. It is usually seen in immunocompromised adults. It usually manifests as generalized skin lesions, and most patients respond to Acyclovir treatment. Very few cases have been reported where the infection progresses to involve the lungs. Here we present a case of a young female with a history of uncontrolled human immunodeficiency virus (HIV) infection who presented with diffuse skin lesions that were tested positive for VZV. Despite starting on an appropriate regimen with Intravenous Acyclovir, the patient progressed to develop severe pneumonia and respiratory failure.</p>","PeriodicalId":93960,"journal":{"name":"Cureus","volume":"17 5","pages":"e84630"},"PeriodicalIF":1.0000,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12132666/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Cureus","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.7759/cureus.84630","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
Abstract
Disseminated varicella zoster virus (VZV) infection is rare in older adults. It is usually seen in immunocompromised adults. It usually manifests as generalized skin lesions, and most patients respond to Acyclovir treatment. Very few cases have been reported where the infection progresses to involve the lungs. Here we present a case of a young female with a history of uncontrolled human immunodeficiency virus (HIV) infection who presented with diffuse skin lesions that were tested positive for VZV. Despite starting on an appropriate regimen with Intravenous Acyclovir, the patient progressed to develop severe pneumonia and respiratory failure.