The role of circadian preferences in the bidirectional link between sleep quality and depressive symptoms: A cross-lagged panel design.

IF 2.2 4区 医学 Q2 BIOLOGY
Ana Petak, Miranda Novak
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引用次数: 0

Abstract

Poor sleep quality is strongly linked to depressive symptoms; however, the mediators of this relationship are not well understood. Circadian preferences (CP) emerge as one of the possible mediators underlying this relationship. Previous studies have focused on clinical samples, employed cross-sectional designs and neglected emerging adulthood stage. This study aimed to explore causal relationships using two-wave longitudinal data. The final sample included 272 students from the University of Zagreb (79% female), aged between 18 and 25 years (M = 20.08, SD = 1.14). The Cross-Lagged Panel Model (CLPM) with mediation was employed to test the bidirectional link between sleep quality and depressive symptoms, considering the mediating effect of CP. According to the results, the relationship between sleep quality and depressive symptoms is reciprocal. The effect size indicates that sleep quality has a statistically significant predictive effect on depressive symptoms over time, and vice versa. Mediation analysis revealed that CP did not significantly mediate the relationship between sleep quality and depressive symptoms. CP significantly influenced sleep quality but did not independently contribute to depressive symptoms, suggesting that other mechanisms may be involved in this relationship, such as genetic influences or emotional regulation. The bidirectional relationship between sleep quality and depressive symptoms has significant implications for effective treatment and the prevention of future issues and poorer prognoses. Environmental interventions designed to enhance sleep quality may prevent the onset of depression or reduce existing depressive symptoms. To maximize the effectiveness of these interventions, further research into the mediators of this relationship is essential.

昼夜节律偏好在睡眠质量和抑郁症状之间的双向联系中的作用:一个交叉滞后的面板设计
睡眠质量差与抑郁症状密切相关;然而,这种关系的中介并没有得到很好的理解。昼夜节律偏好(CP)作为这种关系的可能中介之一出现。以往的研究主要集中在临床样本上,采用横断面设计,忽视了初成年期。本研究旨在利用两波纵向数据探讨因果关系。最终样本包括来自萨格勒布大学的272名学生(79%为女性),年龄在18至25岁之间(M = 20.08, SD = 1.14)。考虑CP的中介作用,采用具有中介作用的交叉滞后面板模型(cross - lag Panel Model, CLPM)检验睡眠质量与抑郁症状之间的双向联系。结果表明,睡眠质量与抑郁症状之间存在相互关系。效应大小表明,随着时间的推移,睡眠质量对抑郁症状有统计学上显著的预测作用,反之亦然。中介分析显示CP对睡眠质量与抑郁症状的关系无显著中介作用。CP会显著影响睡眠质量,但不会独立导致抑郁症状,这表明这种关系可能涉及其他机制,如遗传影响或情绪调节。睡眠质量和抑郁症状之间的双向关系对有效治疗和预防未来问题和不良预后具有重要意义。旨在提高睡眠质量的环境干预可能会预防抑郁症的发作或减轻现有的抑郁症状。为了最大限度地提高这些干预措施的有效性,对这种关系的中介进行进一步研究是必不可少的。
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来源期刊
Chronobiology International
Chronobiology International 生物-生理学
CiteScore
5.60
自引率
7.10%
发文量
110
审稿时长
1 months
期刊介绍: Chronobiology International is the journal of biological and medical rhythm research. It is a transdisciplinary journal focusing on biological rhythm phenomena of all life forms. The journal publishes groundbreaking articles plus authoritative review papers, short communications of work in progress, case studies, and letters to the editor, for example, on genetic and molecular mechanisms of insect, animal and human biological timekeeping, including melatonin and pineal gland rhythms. It also publishes applied topics, for example, shiftwork, chronotypes, and associated personality traits; chronobiology and chronotherapy of sleep, cardiovascular, pulmonary, psychiatric, and other medical conditions. Articles in the journal pertain to basic and applied chronobiology, and to methods, statistics, and instrumentation for biological rhythm study. Read More: http://informahealthcare.com/page/cbi/Description
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