Current state and future directions of interventions for neglected tropical diseases

IF 21.4 1区心理学 Q1 MULTIDISCIPLINARY SCIENCES

Nature Human Behaviour Pub Date : 2025-06-04 DOI:10.1038/s41562-025-02219-0

John Owusu Gyapong, Mawuli Gohoho, Alfred Kwesi Manyeh, Mustapha Immurana, Margaret Gyapong

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Abstract

Neglected tropical diseases (NTDs) impose severe health, social and economic burdens on millions in impoverished regions. These diseases, once overlooked, have gained global attention following strategic advocacy and planning by the World Health Organization and its partners, and are now prioritized within the Sustainable Development Goals framework. In this Review, we examine current interventions including preventive chemotherapy, innovative and intensified disease management, vector control, One Health, and improvements in water, sanitation and hygiene; and we highlight the role of human behaviour and community engagement and involvement in driving intervention success, sustainability and ownership within communities. Regional disparities, particularly in sub-Saharan Africa and South Asia, call for tailored approaches that tackle logistical barriers, funding constraints, donor dependency, stigma and drug resistance. To control and eradicate NTDs by 2030, we require sustained political commitment, innovative financing and the greater integration of NTD strategies within broader health systems.

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被忽视的热带病干预措施的现状和未来方向

被忽视的热带病给贫困地区数百万人带来了严重的健康、社会和经济负担。这些疾病一度被忽视，但在世界卫生组织及其合作伙伴的战略宣传和规划之后，已获得全球关注，现在已成为可持续发展目标框架内的优先事项。在这篇综述中，我们研究了目前的干预措施，包括预防性化疗、创新和强化的疾病管理、媒介控制、同一个健康，以及改善水、环境卫生和个人卫生；我们强调人类行为和社区参与在推动社区干预成功、可持续性和所有权方面的作用。区域差异，特别是在撒哈拉以南非洲和南亚，要求采取有针对性的方法来解决后勤障碍、资金限制、捐助者依赖、污名化和耐药性问题。为了到2030年控制和根除被忽视的热带病，我们需要持续的政治承诺、创新的融资方式以及将被忽视的热带病战略更大程度地纳入更广泛的卫生系统。

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来源期刊

Nature Human Behaviour Psychology-Social Psychology

CiteScore

36.80

自引率

1.00%

发文量

227

期刊介绍： Nature Human Behaviour is a journal that focuses on publishing research of outstanding significance into any aspect of human behavior.The research can cover various areas such as psychological, biological, and social bases of human behavior.It also includes the study of origins, development, and disorders related to human behavior.The primary aim of the journal is to increase the visibility of research in the field and enhance its societal reach and impact.