[Prevalence and characteristics of risk factors for cerebrovascular disease in overweight].

Q3 Medicine

Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova Pub Date : 2025-01-01 DOI:10.17116/jnevro2025125051118

I T Murkamilov, K A Aitbaev, V V Fomin, F A Yusupov, Z F Yusupova, T F Yusupova, Zh I Solizhonov, Y R Boymurodov

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引用次数: 0

Abstract

Aim: To study the frequency of modifiable risk factors for cerebrovascular disease (CVD) in overweight (OW) males and females.

Materials and methods: The medical records of 522 overweight somatic patients were reviewed. The mean age was 54 years (18-86 years). The frequency of modifiable risk factors and CVD progression were assessed. Patients were divided into two groups: overweight males (n=258) and females (n=264).

Results: Hypertension (36.2%), coronary heart disease (17.2%), and chronic obstructive pulmonary disease (16.4%) were most commonly diagnosed in overweight patients. In males, creatinine [87.0 (74.2; 109.0) µmol/L vs. 69.2 (60.0; 83.4) µmol/L, p<0.05], hemoglobin levels (146.1±25.8 g/L vs. 130.6±19.6 g/L, p<0.05), and red blood cell counts (5.01±0.89·10¹²/L vs. 4.63±0.67·10¹²/L, p<0.05) were significantly higher than in females. Females had higher platelet counts (301.2±106.1·10⁹L vs 270.8±86.2·10⁹L, p<0.05) and high-density lipoprotein cholesterol (1.22±0.25 mmol/L vs 1.08±0.32 mmol/L, p<0.05). In all overweight patients, the most common risk factors were tachycardia (>80 bpm at rest, 41.5%), hypertension (31.2%), hypercholesterolemia (28.9%), and dyslipidemia (26.8%). The prevalence of anemia, hyperglycemia, and hypertriglyceridemia was 13.2%, 14.5%, and 16.2%, respectively. F. Hoek's equations with cystatin C revealed more patients with impaired renal excretory function. Body mass index (BMI) correlated with diastolic blood pressure and triglyceride levels in males. In females, BMI was associated with systolic, mean, and pulse blood pressure, glucose and total cholesterol levels, and proteinuria.

Conclusion: In overweight males and females, high blood pressure, impaired lipid-carbohydrate metabolism, reduced renal excretory function, and proteinuria were common modifiable risk factors for CVD. In females, BMI is strongly associated with hypertension, hyperglycemia, hypercholesterolemia, and proteinuria.

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[超重人群脑血管疾病的患病率及危险因素特征]。

目的：研究超重（OW）男性和女性脑血管病（CVD）可改变危险因素的频率。材料与方法：回顾性分析522例超重躯体患者的病历资料。平均年龄54岁（18 ~ 86岁）。评估可改变危险因素和心血管疾病进展的频率。患者分为两组：超重男性（258例）和女性（264例）。结果：超重患者最常诊断为高血压（36.2%）、冠心病（17.2%）和慢性阻塞性肺疾病（16.4%）。男性肌酐[87.0 (74.2；109.0)µmol/L vs. 69.2 (60.0；血红蛋白水平（146.1±25.8 g/L vs. 130.6±19.6 g/L, p0.05）、红细胞计数（5.01±0.89·1012/L vs. 4.63±0.67·1012/L, p0.05）显著高于女性。女性血小板计数（301.2±106.1·109L vs 270.8±86.2·109L, p0.05）和高密度脂蛋白胆固醇（1.22±0.25 mmol/L vs 1.08±0.32 mmol/L, p0.05）较高。在所有超重患者中，最常见的危险因素是心动过速（静息时bbb80bpm， 41.5%）、高血压（31.2%）、高胆固醇血症（28.9%）和血脂异常（26.8%）。贫血、高血糖和高甘油三酯血症的患病率分别为13.2%、14.5%和16.2%。F. Hoek与胱抑素C的方程显示肾脏排泄功能受损的患者较多。体重指数（BMI）与男性舒张压和甘油三酯水平相关。在女性中，BMI与收缩压、平均血压和脉搏血压、葡萄糖和总胆固醇水平以及蛋白尿有关。结论：在超重的男性和女性中，高血压、脂-碳水化合物代谢受损、肾脏排泄功能下降和蛋白尿是心血管疾病常见的可改变的危险因素。在女性中，BMI与高血压、高血糖、高胆固醇血症和蛋白尿密切相关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Zhurnal Nevrologii I Psikhiatrii Imeni S S Korsakova 医学-精神病学

CiteScore

1.10

自引率

0.00%

发文量

287

审稿时长

3-6 weeks

期刊介绍： Одно из старейших медицинских изданий России, основанное в 1901 году. Создание журнала связано с именами выдающихся деятелей отечественной медицины, вошедших в историю мировой психиатрии и неврологии, – С.С. Корсакова и А.Я. Кожевникова. Широкий диапазон предлагаемых журналом материалов и разнообразие форм их представления привлекают внимание научных работников и врачей, опытных и начинающих медиков, причем не только неврологов и психиатров, но и специалистов смежных областей медицины.