Purpuric pityriasis rosea in patients with anorexia nervosa.

IF 1.3 Q2 DERMATOLOGY
Dermatology Reports Pub Date : 2025-08-22 Epub Date: 2025-01-20 DOI:10.4081/dr.2025.10053
Giulia Ciccarese, Antonio Guadagno, Astrid Herzum, Valentina Amicarelli, Francesco Drago
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Abstract

Pityriasis rosea (PR) is an exanthematous disease associated with the endogenous systemic reactivation of human herpesvirus (HHV)-6 and/or HHV-7. Variants of PR characterized by atypical lesion morphology, eruption course, and severe symptoms have already been described, but their prevalence is probably underestimated. We report herein two patients suffering from anorexia nervosa (AN) who developed a very rare form of purpuric PR. So far, no cases of PR in AN patients have been reported in the literature.

Abstract Image

Abstract Image

紫癜性糠疹多发于神经性厌食症患者。
玫瑰糠疹(PR)是一种与人疱疹病毒(HHV)-6和/或HHV-7内源性全身再激活相关的疹性疾病。以非典型病变形态、爆发过程和严重症状为特征的PR变异已经被描述过,但其患病率可能被低估了。我们在此报告两例神经性厌食症(AN)患者发展为一种非常罕见的紫癜性PR。到目前为止,文献中尚未报道AN患者发生PR的病例。在AN中,受损的细胞介导的免疫可能有利于HHV- 6和/或HHV-7的内源性全身再激活,从而导致PR。此外,血管细胞粘附分子1、白细胞介素6和肿瘤坏死因子-α的水平升高已在AN患者中被证实,这可能是血管功能障碍增加的原因。
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来源期刊
Dermatology Reports
Dermatology Reports DERMATOLOGY-
CiteScore
1.40
自引率
0.00%
发文量
74
审稿时长
10 weeks
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