Seonghyuk Park, Youngtaek Kim, Jungseub Lee, Sangmin Jung, Jongho Hong, Suryong Kim, Seung-Ryeol Lee, Jiyoung Song, Siwan Park, Young Sun Oh, Jihoon Ko, Noo Li Jeon
{"title":"Flow-IMPACT: A Pumpless, High-Throughput 3D Cell Culture Platform for Investigation of Synergistic Angiogenic Effects (Adv. Mater. Technol. 11/2025)","authors":"Seonghyuk Park, Youngtaek Kim, Jungseub Lee, Sangmin Jung, Jongho Hong, Suryong Kim, Seung-Ryeol Lee, Jiyoung Song, Siwan Park, Young Sun Oh, Jihoon Ko, Noo Li Jeon","doi":"10.1002/admt.202570060","DOIUrl":null,"url":null,"abstract":"<p><b>Flow-IMPACT</b></p><p>In article number 2401526, Noo Li Jeon and co-workers implement a pumpless microfluidic platform that stably reproduces interstitial flow within physiological velocity ranges. Such flow is achieved through engineered hydraulic resistance using serpentine channels and hydrogels. The study elucidates how flow-mediated transport and mechanical cues regulate vascularization, providing a valuable framework for microenvironmental and tissue engineering research.\n\n <figure>\n <div><picture>\n <source></source></picture><p></p>\n </div>\n </figure></p>","PeriodicalId":7292,"journal":{"name":"Advanced Materials Technologies","volume":"10 11","pages":""},"PeriodicalIF":6.4000,"publicationDate":"2025-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/admt.202570060","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Advanced Materials Technologies","FirstCategoryId":"88","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/admt.202570060","RegionNum":3,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MATERIALS SCIENCE, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Flow-IMPACT
In article number 2401526, Noo Li Jeon and co-workers implement a pumpless microfluidic platform that stably reproduces interstitial flow within physiological velocity ranges. Such flow is achieved through engineered hydraulic resistance using serpentine channels and hydrogels. The study elucidates how flow-mediated transport and mechanical cues regulate vascularization, providing a valuable framework for microenvironmental and tissue engineering research.
期刊介绍:
Advanced Materials Technologies Advanced Materials Technologies is the new home for all technology-related materials applications research, with particular focus on advanced device design, fabrication and integration, as well as new technologies based on novel materials. It bridges the gap between fundamental laboratory research and industry.