Trends in cancer incidence and mortality in Italy, 2013–2017

IF 2.4 3区医学 Q3 ONCOLOGY

Cancer Epidemiology Pub Date : 2025-06-03 DOI:10.1016/j.canep.2025.102855

Viviana Perotti , Andrea Tittarelli , Paolo Contiero , Luigino Dal Maso , Maria Teresa Pesce , Maurizio Zarcone , Alessio Gili , Walter Mazzucco , Fabrizio Stracci , Emanuele Crocetti , Sabrina Fabiano

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Abstract

Cancer incidence and mortality trends represent epidemiological indicators of fundamental importance for public health systems. The study's aim is to present recent (2013–2017) short-term cancer incidence and mortality trends in Italy, including 80 % of the Italian population, for different cancer sites by sex, age group, and areas. Joinpoint Regression models were employed. A significantly decreasing trend in the incidence of all cancers was observed for men in Italy (-1.9 % per year), particularly for cancers of the lung (-2.5 %), liver (-3.9 %), stomach (-2.8 %), colorectal (-2.2 %), prostate (-3.4 %), and leukaemias (-3.2 %). The only significant increase was seen for skin melanoma (+5.2 % per year). Among women, overall cancer incidence remained stable, with a decrease in the North (-0.6 %) and an increase in the South and Islands (+0.9 %). Decreasing trends were observed for colorectal (-1.9 %), stomach (-3.5 %), liver (-4.0 %%), and leukaemias (-2.0 %) cancers, while incidence increased for skin melanoma (+6.0 % per year), and lung cancer (2.3 %). Cancer mortality declined consistently in both sexes (-1.8 % per year in men and −0.6 % in women), across different areas, and age groups. The observed trends in men and women partly reflect the impact of risk factors affecting both sexes at different times, mainly in the case of tobacco and lung cancer. Also, some trends may be linked to organized screening initiatives (e.g. colorectal) or the decrease in opportunistic screening (e.g. prostate). The snapshot of cancer trends in Italy may highlight new opportunities for strengthening prevention activities and advancing research on early detection and target treatments.

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2013-2017年意大利癌症发病率和死亡率趋势

癌症发病率和死亡率趋势是对公共卫生系统至关重要的流行病学指标。该研究的目的是介绍意大利近期（2013-2017年）短期癌症发病率和死亡率趋势，包括80% %的意大利人口，按性别、年龄组和地区划分不同的癌症部位。采用Joinpoint回归模型。意大利男性所有癌症的发病率都有显著下降趋势（每年-1.9 %），特别是肺癌（-2.5 %）、肝癌（-3.9 %）、胃癌（-2.8 %）、结直肠癌（-2.2 %）、前列腺癌（-3.4 %）和白血病（-3.2 %）。唯一显著增加的是皮肤黑色素瘤（每年+ 5.2% %）。在妇女中，总体癌症发病率保持稳定，北部下降（-0.6 %），南部和岛屿增加（+0.9 %）。结直肠癌（-1.9 %）、胃癌（-3.5 %）、肝癌（-4.0 %%）和白血病（-2.0 %）的发病率呈下降趋势，而皮肤黑色素瘤（每年+6.0 %）和肺癌（2.3 %）的发病率呈上升趋势。在不同地区和年龄组，男女癌症死亡率持续下降（男性每年-1.8 %，女性每年- 0.6 %）。在男性和女性中观察到的趋势部分反映了在不同时期影响两性的风险因素的影响，主要是烟草和肺癌。此外，一些趋势可能与有组织的筛查举措（如结肠直肠癌）或机会性筛查（如前列腺癌）的减少有关。意大利癌症趋势概览可能突出加强预防活动和推进早期发现和靶向治疗研究的新机会。

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来源期刊

Cancer Epidemiology 医学-肿瘤学

CiteScore

4.50

自引率

3.80%

发文量

200

审稿时长

39 days

期刊介绍： Cancer Epidemiology is dedicated to increasing understanding about cancer causes, prevention and control. The scope of the journal embraces all aspects of cancer epidemiology including: • Descriptive epidemiology • Studies of risk factors for disease initiation, development and prognosis • Screening and early detection • Prevention and control • Methodological issues The journal publishes original research articles (full length and short reports), systematic reviews and meta-analyses, editorials, commentaries and letters to the editor commenting on previously published research.