DNA barcoding shows that Toxocara cati infecting domestic and wild felids is a species complex

IF 2.2 2区农林科学 Q2 PARASITOLOGY

Veterinary parasitology Pub Date : 2025-05-30 DOI:10.1016/j.vetpar.2025.110514

Renata Fogt-Wyrwas , Miroslawa Dabert , Wojciech Jarosz

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Abstract

The insufficient attention paid to the importance of Toxocara cati in the epidemiology of toxocariasis has resulted in significant gaps in the understanding of the true zoonotic potential of this parasite. Therefore, further research is necessary to understand its biology and epidemiology. In this article, the hypothesis of possible speciation in the T. cati complex was tested using cox1 sequences from T. cati individuals infecting domestic and wild felids from different parts of the world. Using DNA barcoding, a phylogenetic analysis was performed that grouped T. cati representatives into five clades according to the host species. The differences in cox1 sequences between T. cati from domestic cats and T. cati from wild felids were substantial (6.68 %–10.84 %). The results of the Assemble Species by Automatic Partitioning analysis supported the species status of the clades. However, the determination of the actual species diversity of the T. cati complex would necessitate an analysis of a wider range of wild hosts. A detailed understanding of the genetic diversity and phylogenetic relationships between species in the T. cati complex will contribute to more accurate identification, diagnosis and better control of these parasites.

查看原文本刊更多论文

DNA条形码显示猫弓形虫感染家养和野生猫科动物是一个物种复合体

由于对猫弓形虫在弓形虫病流行病学中的重要性重视不够，导致对这种寄生虫真正的人畜共患潜力的认识存在重大差距。因此，有必要进一步研究其生物学和流行病学。本文利用感染世界不同地区家养和野生猫的猫绦虫个体的cox1序列，对猫绦虫复合体可能形成的假设进行了检验。利用DNA条形码进行系统发育分析，根据寄主种类将猫粉虱代表分为5个支系。家猫与野地猫的cox1序列差异较大（6.68 % ~ 10.84 %）。自动划分的结果支持了支系的物种地位。然而，要确定猫舌虫复合体的实际物种多样性，需要对更大范围的野生寄主进行分析。深入了解猫舌虫复合体的遗传多样性和物种间的系统发育关系，将有助于更准确地识别、诊断和更好地控制这些寄生虫。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Veterinary parasitology 农林科学-寄生虫学

CiteScore

5.30

自引率

7.70%

发文量

126

审稿时长

36 days

期刊介绍： The journal Veterinary Parasitology has an open access mirror journal,Veterinary Parasitology: X, sharing the same aims and scope, editorial team, submission system and rigorous peer review. This journal is concerned with those aspects of helminthology, protozoology and entomology which are of interest to animal health investigators, veterinary practitioners and others with a special interest in parasitology. Papers of the highest quality dealing with all aspects of disease prevention, pathology, treatment, epidemiology, and control of parasites in all domesticated animals, fall within the scope of the journal. Papers of geographically limited (local) interest which are not of interest to an international audience will not be accepted. Authors who submit papers based on local data will need to indicate why their paper is relevant to a broader readership. Parasitological studies on laboratory animals fall within the scope of the journal only if they provide a reasonably close model of a disease of domestic animals. Additionally the journal will consider papers relating to wildlife species where they may act as disease reservoirs to domestic animals, or as a zoonotic reservoir. Case studies considered to be unique or of specific interest to the journal, will also be considered on occasions at the Editors'' discretion. Papers dealing exclusively with the taxonomy of parasites do not fall within the scope of the journal.