Superparamagnetic hydrogels: Precision-driven platforms for biomedicine, robotics, and environmental remediation

Huaibin Wang , Yingying Hou , Long Chen , Weihong Mo , Leyan Xuan , Jialin Wu , Jie Wang , Maobin Xie , Shufang Wang , Guosheng Tang
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Abstract

Hydrogels are widely recognized for their biocompatibility and structural adaptability in regenerative medicine and three-dimensional (3D) bioprinting, yet their inherent static nature fundamentally limits applications demanding dynamic spatiotemporal control. The incorporation of superparamagnetic iron oxide nanoparticles (SPIONs) addresses this issue. The incorporation of SPIONs enables real-time programmable manipulation through magnetic field gradients. This amalgamation not only endows hydrogels with abilities such as magnetic propulsion, positioning, magnetoguidance, movement, and levitation, typical of magnetic materials, but also introduces novel functionalities like responsiveness to thermal effects and enhanced adsorption capabilities. This review delves into the transformative potential unlocked by the integration of SPIONs into hydrogels, showcasing their unique functional enhancements and targeted applications in robotics, precision medicine, and wastewater treatment.
超顺磁水凝胶:用于生物医学、机器人和环境修复的精密驱动平台
水凝胶因其生物相容性和结构适应性在再生医学和三维生物打印中得到广泛认可,但其固有的静态特性从根本上限制了需要动态时空控制的应用。超顺磁性氧化铁纳米颗粒(SPIONs)的加入解决了这个问题。SPIONs的结合可以通过磁场梯度实现实时可编程操作。这种融合不仅赋予了水凝胶磁性材料的磁性推进、定位、磁导向、运动和悬浮等能力,而且还引入了新的功能,如对热效应的响应和增强的吸附能力。这篇综述深入探讨了将SPIONs集成到水凝胶中所释放的变革潜力,展示了它们独特的功能增强以及在机器人、精准医疗和废水处理方面的针对性应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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