Time to exercise! Boosting exercise performance via AMPK signaling

IF 27.7 1区生物学 Q1 CELL BIOLOGY

Cell metabolism Pub Date : 2025-06-03 DOI:10.1016/j.cmet.2025.05.003

Tinh-Hai Collet, Charna Dibner

引用次数: 0

Abstract

Body physiology follows the daily rhythm driven by the circadian system, which underlies the emerging concept of chrono-medicine. In this issue, Chen et al.¹ report that feeding timing modulates adipocyte AMP-activated protein kinase (AMPK) α2 signaling to enhance exercise performance in mice, paving the way for chronotherapeutic approaches of AMPK activators such as metformin.

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是时候锻炼了！通过AMPK信号传导提高运动表现

身体生理遵循由昼夜节律系统驱动的日常节奏，这是新兴的时间医学概念的基础。在这期杂志上，Chen等人报道了进食时间调节脂肪细胞amp活化蛋白激酶(AMPK) α2信号以提高小鼠的运动表现，为二甲双胍等AMPK激活剂的时间治疗方法铺平了道路。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell metabolism 生物-内分泌学与代谢

CiteScore

48.60

自引率

1.40%

发文量

173

审稿时长

2.5 months

期刊介绍： Cell Metabolism is a top research journal established in 2005 that focuses on publishing original and impactful papers in the field of metabolic research.It covers a wide range of topics including diabetes, obesity, cardiovascular biology, aging and stress responses, circadian biology, and many others. Cell Metabolism aims to contribute to the advancement of metabolic research by providing a platform for the publication and dissemination of high-quality research and thought-provoking articles.