Comparison of the effects of ice saline and kangfuxin mouthwash on improving oral infection following buccal mucosa resection.

Oral and maxillofacial surgery Pub Date : 2025-06-02 DOI:10.1007/s10006-025-01402-x

Yu Zhang, Chuanrui Yang, Lu Tang, Dandan Xie, Yulong Yi, Lei Lei, Li Xue

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Abstract

Objective: This study aimed to compare the efficacy of ice saline and Kangfuxin mouthwash in reducing oral infection incidence following buccal mucosa resection in patients.

Methods: A retrospective analysis was performed on patients who underwent buccal mucosa resection at a tertiary hospital's Urology Department from January 2020 to December 2024. Post-surgery, patients used ice saline and Kangfuxin mouthwash for six mouthwashes before and after meals, with 10 ml per use, gargling for 3 min each time. The incidence of oral infection was compared between the two groups using t-tests, chi-square tests, and non-parametric tests.

Results: A total of 228 patients were included, with an overall oral infection incidence of 9.6%. After balancing the baseline characteristics and nutritional indicators between the groups, a statistically significant difference was observed in infection incidence and pain scores on the third postoperative day (p < 0.05).

Conclusion: Addressing oral infection in patients following buccal mucosa resection is crucial; postoperative use of Kangfuxin mouthwash shows potential in reducing oral infection incidence.

Clinical trial number: Not applicable.

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冰盐水与康复新漱口水对口腔黏膜切除术后口腔感染的改善效果比较。

目的：比较冰生理盐水与康复新漱口水对口腔黏膜切除术后患者口腔感染发生率的影响。方法：回顾性分析2020年1月至2024年12月在某三级医院泌尿外科行口腔黏膜切除术的患者。术后患者餐前餐后分别用冰生理盐水和康复新漱口水漱口6次，每次10毫升，每次漱口3分钟。采用t检验、卡方检验和非参数检验比较两组口腔感染发生率。结果：共纳入228例患者，口腔感染总发生率为9.6%。在平衡各组的基线特征和营养指标后，术后第3天感染发生率和疼痛评分差异有统计学意义(p)。结论：口腔黏膜切除术后患者口腔感染的处理至关重要；术后使用康复新漱口水有降低口腔感染发生率的潜力。临床试验号：不适用。

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Oral and maxillofacial surgery

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