Safety and efficacy of platelet-rich plasma in the treatment of periorbital skin photoaging.

IF 1.3 4区 医学 Q3 DERMATOLOGY
Journal of Cosmetic and Laser Therapy Pub Date : 2025-01-01 Epub Date: 2025-06-02 DOI:10.1080/14764172.2025.2513380
Xin-Li, Lingling-Hu, Weimin-Song, Qian-Lu
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引用次数: 0

Abstract

Periorbital skin photoaging is a common cosmetic problem.Presently, conventional treatment methods cannot achieve satisfactory results. Periorbital skin aging may benefit from platelet-rich plasma (PRP) injection. However, there is little experimental evidence on the safety and efficacy of PRP in the treatment of periorbital skin photoaging. To examine the safety and efficacy of PRP injection in the treatment of periorbital skin photoaging, PRP was injected into the periorbital skin of 20 patients, and patient satisfaction was assessed at the first month (M1), the second month (M2), and the third month (M3) after treatment. Two experienced dermatologists independently evaluated the patient's skin before and after treatment according to internationally accepted guidelines. The objective indicators of skin hydration, melanin index, erythema index, skin brightness, transepidermal water loss (TEWL), skin elasticity, and skin thickness were measured. Some subjective indicators, including pigmentation around the eyes, suborbital wrinkles, and static crow's feet, were significantly improved. Some objective indicators, including skin brightness, skin thickness, and collagen strength, were also significantly improved. Eye bags and TEWL slightly improved, but the differences were not statistically significant. The overall patient satisfaction with the treatment was high, no serious complications were noted, and the recovery profile was favorable. PRP injection was safe and effective for the treatment of periorbital skin photoaging.

富血小板血浆治疗眶周皮肤光老化的安全性和有效性。
眶周皮肤光老化是一个常见的美容问题。目前,常规的治疗方法不能达到满意的效果。富血小板血浆(PRP)注射可能对眼眶周围皮肤老化有益。然而,关于PRP治疗眶周皮肤光老化的安全性和有效性的实验证据很少。为探讨PRP注射液治疗眶周皮肤光老化的安全性和有效性,对20例患者眼眶周皮肤注射PRP,并于治疗后第1个月(M1)、第2个月(M2)、第3个月(M3)评估患者满意度。两位经验丰富的皮肤科医生根据国际公认的指导方针独立评估患者治疗前后的皮肤。测量皮肤水合、黑色素指数、红斑指数、皮肤亮度、经皮失水(TEWL)、皮肤弹性、皮肤厚度等客观指标。一些主观指标,包括眼睛周围的色素沉着、眶下皱纹和静态鱼尾纹,都有了明显的改善。一些客观指标,包括皮肤亮度,皮肤厚度,胶原蛋白强度也有明显改善。眼袋和TEWL略有改善,但差异无统计学意义。患者对治疗总体满意度高,无严重并发症发生,恢复情况良好。PRP注射治疗眶周皮肤光老化安全有效。
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来源期刊
CiteScore
2.50
自引率
0.00%
发文量
36
审稿时长
>12 weeks
期刊介绍: A unique journal that focuses on the application of cosmetic laser and light therapies on the skin. The Journal of Cosmetic & Laser Therapy provides a forum for stimulating and up-to-date studies demonstrating the wide range of therapeutic options for clinicians and surgeons involved in cosmetic and dermatological treatment. The journal is aimed at dermatologists, cosmetic surgeons, plastic and facial plastic surgeons, oculoplastic surgeons and all those interested in the rapidly expanding field of cosmetic and laser therapy. Features include: -Cosmetic surgery, including facial rejuvenation, hair removal and skin resurfacing -Use of lasers and other light sources for cosmetic and dermatological treatment -Applications of peeling agents, fillers, injectables, implants and other cosmetic modalities -Topical treatments -Practical tips and safety issues
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