Resection of Midfacial Tumors Assisted by Virtual Planning Based on CT/MRI Multimodal Image Fusion: A Cohort Study.

IF 0.6 Q4 DENTISTRY, ORAL SURGERY & MEDICINE

Journal of Maxillofacial & Oral Surgery Pub Date : 2025-06-01 Epub Date: 2025-01-19 DOI:10.1007/s12663-025-02441-3

Lei-Hao Hu, Wei Zhou, Wen-Bo Zhang, Yao Yu, Zhi-Peng Sun, Xin Peng

{"title":"Resection of Midfacial Tumors Assisted by Virtual Planning Based on CT/MRI Multimodal Image Fusion: A Cohort Study.","authors":"Lei-Hao Hu, Wei Zhou, Wen-Bo Zhang, Yao Yu, Zhi-Peng Sun, Xin Peng","doi":"10.1007/s12663-025-02441-3","DOIUrl":null,"url":null,"abstract":"Objective: This cohort study aimed to preliminarily explore the effect of midfacial tumor resection procedure with assistance of virtual planning based on CT/MRI multimodal image fusion.Methods: For the experimental cohort, patients with midfacial tumors receiving treatment from February 2019 to March 2021 were enrolled. Virtual planning was completed preoperatively based on CT/MRI multimodal image fusion. Tumor resection was performed under virtual planning-based surgical navigation, and intraoperative frozen sections were taken to determine resection margin status. For the control cohort, patients with midfacial tumors treated by the same surgical team were enrolled according to the same criteria. Patients underwent surgery assisted by virtual planning based on single-modality CT images. Resection margin and survival status were compared between groups during follow-up.Results: Altogether twenty-nine patients were enrolled. The resection margin status was significantly different between groups at the per-margin level (experimental group: 100% [66/66] negative; control group: 90.9% negative [70/77]; P = 0.014). During follow-up period, two patients in experimental cohort and seven patients in control cohort confirmed local recurrence.Conclusions: Patients with midfacial tumor who underwent virtual planning based on CT/MRI multimodal image fusion were more likely to have tumor-free resection margins. The use of the image fusion procedure may improve treatment outcomes in such patients.","PeriodicalId":47495,"journal":{"name":"Journal of Maxillofacial & Oral Surgery","volume":"24 3","pages":"674-684"},"PeriodicalIF":0.6000,"publicationDate":"2025-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12122973/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Maxillofacial & Oral Surgery","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s12663-025-02441-3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/19 0:00:00","PubModel":"Epub","JCR":"Q4","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: This cohort study aimed to preliminarily explore the effect of midfacial tumor resection procedure with assistance of virtual planning based on CT/MRI multimodal image fusion.

Methods: For the experimental cohort, patients with midfacial tumors receiving treatment from February 2019 to March 2021 were enrolled. Virtual planning was completed preoperatively based on CT/MRI multimodal image fusion. Tumor resection was performed under virtual planning-based surgical navigation, and intraoperative frozen sections were taken to determine resection margin status. For the control cohort, patients with midfacial tumors treated by the same surgical team were enrolled according to the same criteria. Patients underwent surgery assisted by virtual planning based on single-modality CT images. Resection margin and survival status were compared between groups during follow-up.

Results: Altogether twenty-nine patients were enrolled. The resection margin status was significantly different between groups at the per-margin level (experimental group: 100% [66/66] negative; control group: 90.9% negative [70/77]; P = 0.014). During follow-up period, two patients in experimental cohort and seven patients in control cohort confirmed local recurrence.

Conclusions: Patients with midfacial tumor who underwent virtual planning based on CT/MRI multimodal image fusion were more likely to have tumor-free resection margins. The use of the image fusion procedure may improve treatment outcomes in such patients.

查看原文本刊更多论文

基于CT/MRI多模态图像融合的虚拟规划辅助面部正中肿瘤切除术：一项队列研究。

目的：本队列研究旨在初步探讨基于CT/MRI多模态图像融合的虚拟规划辅助面部正中肿瘤切除手术的效果。方法：实验队列纳入2019年2月至2021年3月接受治疗的面部正中肿瘤患者。术前基于CT/MRI多模态图像融合完成虚拟规划。在基于虚拟计划的手术导航下进行肿瘤切除，术中冰冻切片确定切除边缘状态。对于对照组，根据相同的标准纳入同一手术小组治疗的面部中肿瘤患者。患者接受基于单模态CT图像的虚拟计划辅助手术。随访期间比较两组患者切除切缘及生存状况。结果：共纳入29例患者。在每切缘水平上，两组间切缘状态差异有统计学意义(实验组：100%[66/66]阴性；对照组：阴性90.9% [70/77]；p = 0.014)。随访期间，实验组2例，对照组7例局部复发。结论：基于CT/MRI多模态图像融合进行虚拟规划的面中肿瘤患者更有可能获得无瘤切除边缘。使用图像融合程序可以改善这类患者的治疗结果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Journal of Maxillofacial & Oral Surgery DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

1.90

自引率

0.00%

发文量

138

期刊介绍： This journal offers comprehensive coverage of new techniques, important developments and innovative ideas in Oral and Maxillofacial Surgery. Practice-applicable articles help develop the methods used to handle dentoalveolar surgery, facial injuries and deformities, TMJ disorders, oral cancer, jaw reconstruction, anesthesia and analgesia. The journal also includes specifics on new instruments, diagnostic equipment’s and modern therapeutic drugs and devices. Journal of Oral and Maxillofacial Surgery is recommended for first or priority subscription by the Dental Section of the Medical Library Association. Specific topics covered recently have included: ? distraction osteogenesis ? synthetic bone substitutes ? fibroblast growth factors ? fetal wound healing ? skull base surgery ? computer-assisted surgery ? vascularized bone grafts Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services.