Adenomatoid Odontogenic Tumor: Histomorphological Evidence of Its Origin from the Cystic Component and Literature Review.

IF 0.6 Q4 DENTISTRY, ORAL SURGERY & MEDICINE
Journal of Maxillofacial & Oral Surgery Pub Date : 2025-06-01 Epub Date: 2025-03-14 DOI:10.1007/s12663-025-02503-6
Ana Terezinha Marques Mesquita, Gabriela Fonseca Rocha, Karina Helen Martins, Camila de Oliveira Barbeiro, Heitor Albergoni Silveira, Jorge Esquiche León
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引用次数: 0

Abstract

Objectives: Adenomatoid odontogenic tumor (AOT) is a distinct benign odontogenic tumor, with relevant studies indicating that a cystic component can be found in about half of cases; however, controversy still exists regarding its true nature.

Methods: Here, we show an interesting case of follicular AOT affecting the maxilla of a 13-year-old girl, which was predominantly cystic with intraepithelial calcified deposits, including histomorphological changes of its basal and parabasal layers, in close connection with typical AOT nests, the same ones that looked like detach or originate from this cystic component.

Conclusion: Our findings suggest the that the cystic component is part of the tumor in an AOT subgroup, which should also be considered.

腺瘤样牙源性肿瘤:来自囊性成分的组织形态学证据及文献综述。
目的:腺瘤样牙源性肿瘤(Adenomatoid odontogenic tumor, AOT)是一种独特的良性牙源性肿瘤,相关研究表明约半数病例可发现囊性成分;然而,关于其真实性质仍然存在争议。方法:在这里,我们报告了一个有趣的13岁女孩上颌骨的滤泡性AOT病例,主要是囊性的,上皮内钙化沉积,包括其基底层和旁基层的组织形态学改变,与典型的AOT巢密切相关,这些巢看起来像分离或起源于这种囊性成分。结论:我们的研究结果提示,囊性成分是AOT亚组肿瘤的一部分,也应予以考虑。
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来源期刊
Journal of Maxillofacial & Oral Surgery
Journal of Maxillofacial & Oral Surgery DENTISTRY, ORAL SURGERY & MEDICINE-
CiteScore
1.90
自引率
0.00%
发文量
138
期刊介绍: This journal offers comprehensive coverage of new techniques, important developments and innovative ideas in Oral and Maxillofacial Surgery. Practice-applicable articles help develop the methods used to handle dentoalveolar surgery, facial injuries and deformities, TMJ disorders, oral cancer, jaw reconstruction, anesthesia and analgesia. The journal also includes specifics on new instruments, diagnostic equipment’s and modern therapeutic drugs and devices. Journal of Oral and Maxillofacial Surgery is recommended for first or priority subscription by the Dental Section of the Medical Library Association. Specific topics covered recently have included: ? distraction osteogenesis ? synthetic bone substitutes ? fibroblast growth factors ? fetal wound healing ? skull base surgery ? computer-assisted surgery ? vascularized bone grafts Benefits to authorsWe also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services.
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