Hypophosphatemia in Intensive Care Unit Canine Patients: Occurrence and Association With Mortality and Duration of Hospitalization

IF 1.1 4区农林科学 Q3 VETERINARY SCIENCES

Veterinary clinical pathology Pub Date : 2025-06-02 DOI:10.1111/vcp.70013

Ioannis L. Oikonomidis, Paul Rees, Jorge Hernando Sanz, Glynn Woods

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引用次数: 0

Abstract

Background

Hypophosphatemia is commonly observed in unselected human intensive care unit (ICU) patients, and it has been associated, although inconsistently, with worse outcomes and longer duration of hospitalization (DOH). The incidence of hypophosphatemia and its association with mortality and DOH in ICU canine patients is unknown.

Objectives

The aims of this study were to determine the occurrence of hypophosphatemia in unselected ICU canine patients and its association with mortality and DOH.

Methods

The medical records of all dogs admitted to the Teaching Hospital ICU between January 2019 and December 2023 were retrospectively reviewed. Dogs with hypophosphatemia (serum phosphate < 0.9 mmol/L) were identified. For every hypophosphataemic dog included in this study, two age-matched control, non-hypophosphataemic dogs, closely admitted to the ICU in time, were included.

Results

In total, 3233 medical records were reviewed. Hypophosphatemia was noted in ≥ 1 day of hospitalization in 32 dogs (0.99%). The age-matched case and control groups had a median (range) age of 8.0 (1.0–14.0) years. The survival to discharge rates of both hypophosphataemic and control groups were 78% (25/32 and 50/64, respectively), and their DOH (median, 3.5 days; range 1.0–9.0 and median 3.0 days; range 1.0–25.0, respectively) were not significantly different (p = 0.557). Serum phosphate concentration was not correlated with the DOH (p = 0.649).

Conclusions

Hypophosphatemia was noted in only 1% in this canine ICU patient population and was not associated with the survival to discharge and DOH.

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重症监护室犬患者的低磷血症：与死亡率和住院时间的关系

背景：低磷血症常见于未选择的人类重症监护病房（ICU）患者，并且与较差的结局和较长的住院时间（DOH）相关，尽管不一致。低磷血症的发生率及其与ICU犬患者死亡率和DOH的关系尚不清楚。目的：本研究的目的是确定未选择ICU犬患者低磷血症的发生率及其与死亡率和DOH的关系。方法：回顾性分析教学医院ICU 2019年1月至2023年12月收治的所有犬类病历。结果：共回顾了3233份医疗记录。32只（0.99%）狗在住院≥1天出现低磷血症。年龄匹配的病例组和对照组的中位（范围）年龄为8.0（1.0-14.0）岁。低磷血症组和对照组的生存率为78%（分别为25/32和50/64），平均生存时间为3.5天；范围1.0-9.0天，中位数3.0天；范围分别为1.0 ~ 25.0)，差异无统计学意义（p = 0.557）。血清磷酸盐浓度与DOH无相关性（p = 0.649）。结论：在该犬ICU患者中，低磷血症发生率仅为1%，与出院生存率和DOH无关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Veterinary clinical pathology 农林科学-兽医学

CiteScore

1.70

自引率

16.70%

发文量

133

审稿时长

18-36 weeks

期刊介绍： Veterinary Clinical Pathology is the official journal of the American Society for Veterinary Clinical Pathology (ASVCP) and the European Society of Veterinary Clinical Pathology (ESVCP). The journal''s mission is to provide an international forum for communication and discussion of scientific investigations and new developments that advance the art and science of laboratory diagnosis in animals. Veterinary Clinical Pathology welcomes original experimental research and clinical contributions involving domestic, laboratory, avian, and wildlife species in the areas of hematology, hemostasis, immunopathology, clinical chemistry, cytopathology, surgical pathology, toxicology, endocrinology, laboratory and analytical techniques, instrumentation, quality assurance, and clinical pathology education.