Bilateral Asymptomatic Erythematous Plaques on Soles in an Adult Woman

Abstract

A 72-year-old healthy woman presented with bilateral asymptomatic erythematous plaques on her soles, which had persisted for 20 years. Histopathological analysis confirmed the diagnosis of eccrine syringofibroadenoma (ESFA), a rare eccrine cutaneous tumor. It typically appears as slow-growing nodules or plaques, often misdiagnosed due to its rarity. Although generally benign, ESFA requires accurate diagnosis to distinguish it from other entities and to monitor for potential malignant transformation. This case highlights the diagnostic and clinical challenges associated with ESFA and emphasizes the importance of recognizing this rare tumor to guide appropriate management and follow-up.