Prior beetroot juice ingestion prevents the temporal reduction of endothelial function following acute high-intensity resistance exercise

IF 1.3 4区医学 Q4 PHYSIOLOGY

Clinical Physiology and Functional Imaging Pub Date : 2025-06-03 DOI:10.1111/cpf.70014

Takuma Morishima, Sahiro Mizuno, Gaku Murakami, Rikako Yamazaki, Eisuke Ochi

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引用次数: 0

Abstract

Backgrounds

Nutritional strategies for preventing endothelial function impairment following high-intensity resistance exercise remain largely unknown. Considering that beetroot juice (BRJ) ingestion enhances nitric oxide levels, we aimed to evaluate whether prior BRJ ingestion would prevent endothelial function impairment following high-intensity resistance exercise.

Methods

Twelve young males underwent two experimental trials of high-intensity resistance exercise with prior: (1) placebo ingestion (PLA trial) and (2) BRJ ingestion (BRJ trial). All participants ingested 140 mL of PLA or BRJ (approximately 0.0055 or 12.8 mmol of nitrate, respectively) before the high-intensity resistance exercise (leg extension). Participants performed a resistance exercise session comprising five sets of 10 repetitions at 70% of one repetition maximum. During each intervention trial, heart rate (HR) and blood pressure were continuously measured. Brachial artery diameter, velocity, and flow-mediated dilation (FMD) were measured at pre-, 60 min after PLA or BRJ ingestion, and 10 and 60 min after the resistance exercise.

Results

No differences in systolic blood pressure, shear rate, blood flow, and vascular conductance in response to resistance exercise were noted between the trials (p > 0.05). However, at post-10 min after the resistance exercise, the BRJ trial exhibited a greater brachial artery FMD than the PLA trial (p < 0.05). Moreover, the BRJ trial had a significantly higher ΔFMD from pre- to the post-10–min period than the PLA trial (p < 0.05).

Conclusions

BRJ ingestion prevents endothelial function impairment immediately after a high-intensity resistance exercise.

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事先摄入甜菜根汁可防止急性高强度阻力运动后内皮功能的暂时性降低

背景：预防高强度阻力运动后内皮功能损伤的营养策略在很大程度上仍然未知。考虑到摄入甜菜根汁（BRJ）会提高一氧化氮水平，我们的目的是评估事先摄入BRJ是否会预防高强度阻力运动后的内皮功能损伤。方法12名年轻男性进行高强度抗阻运动实验，实验前分别服用安慰剂（PLA试验）和BRJ （BRJ试验）。所有参与者在高强度阻力运动（腿部伸展）前摄入140 mL PLA或BRJ（分别约为0.0055或12.8 mmol硝酸盐）。参与者进行了一项阻力运动，包括五组，每组10次重复，每次最多重复70%。在每次干预试验期间，连续测量心率（HR）和血压。在PLA或BRJ摄入前、60分钟以及阻力运动后10和60分钟测量肱动脉直径、流速和血流介导扩张（FMD）。结果两组抗阻运动后的收缩压、剪切率、血流量和血管导度无显著差异（p > 0.05）。然而，在阻力运动后10分钟，BRJ试验显示肱动脉FMD大于PLA试验（p < 0.05）。此外，BRJ试验在10分钟前至10分钟后的ΔFMD显著高于PLA试验（p < 0.05）。结论：在高强度阻力运动后立即摄入BRJ可防止内皮功能损伤。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Physiology and Functional Imaging 医学-生理学

CiteScore

3.40

自引率

5.60%

发文量

审稿时长

6-12 weeks

期刊介绍： Clinical Physiology and Functional Imaging publishes reports on clinical and experimental research pertinent to human physiology in health and disease. The scope of the Journal is very broad, covering all aspects of the regulatory system in the cardiovascular, renal and pulmonary systems with special emphasis on methodological aspects. The focus for the journal is, however, work that has potential clinical relevance. The Journal also features review articles on recent front-line research within these fields of interest. Covered by the major abstracting services including Current Contents and Science Citation Index, Clinical Physiology and Functional Imaging plays an important role in providing effective and productive communication among clinical physiologists world-wide.