Addressing the challenges of determining fraction metabolized for low turnover drugs – An update from the quantitative fraction metabolized working group of the IQ consortium

IF 2.7 4区医学 Q2 PHARMACOLOGY & PHARMACY

Drug Metabolism and Pharmacokinetics Pub Date : 2025-06-01 DOI:10.1016/j.dmpk.2025.101146

Lawrence Cohen , Priscilla Brun , Upendra Dahal , Angela Doran , Sarah Glass , Niresh Hariparsad , Felix Huth , Gary Jenkins , Charles Locuson , Birk Poller , Lilian Richter , Dustin Smith

引用次数: 0

查看原文本刊更多论文

解决确定低周转率药物代谢分数的挑战-来自IQ联盟定量代谢分数工作组的更新

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

Drug Metabolism and Pharmacokinetics 医学-药学

CiteScore

4.80

自引率

9.50%

发文量

审稿时长

69 days

期刊介绍： DMPK publishes original and innovative scientific papers that address topics broadly related to xenobiotics. The term xenobiotic includes medicinal as well as environmental and agricultural chemicals and macromolecules. The journal is organized into sections as follows: - Drug metabolism / Biotransformation - Pharmacokinetics and pharmacodynamics - Toxicokinetics and toxicodynamics - Drug-drug interaction / Drug-food interaction - Mechanism of drug absorption and disposition (including transporter) - Drug delivery system - Clinical pharmacy and pharmacology - Analytical method - Factors affecting drug metabolism and transport - Expression of genes for drug-metabolizing enzymes and transporters - Pharmacogenetics and pharmacogenomics - Pharmacoepidemiology.