Paeonol crystals from Paeonia suffruticosa Andrews: Extraction, isolation, and multifaceted functional evaluation

IF 2 4区 生物学 Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
Tong Shen, Guisheng Zhang, Mengxian Qiao, Fangmin Guan, Kaiwen Mo, Wenxu Zhang, Ziheng Gao, Haili Zhang
{"title":"Paeonol crystals from Paeonia suffruticosa Andrews: Extraction, isolation, and multifaceted functional evaluation","authors":"Tong Shen,&nbsp;Guisheng Zhang,&nbsp;Mengxian Qiao,&nbsp;Fangmin Guan,&nbsp;Kaiwen Mo,&nbsp;Wenxu Zhang,&nbsp;Ziheng Gao,&nbsp;Haili Zhang","doi":"10.1016/j.bse.2025.105051","DOIUrl":null,"url":null,"abstract":"<div><div><em>Paeonia suffruticosa Andrews</em>, a member of the Paeoniaceae family (formerly classified under Ranunculaceae), is a well-known traditional Chinese medicinal plant. Its dried root bark is rich in paeonol, a bioactive compound with notable antioxidant, anti-hemolytic, bacteriostatic, and anti-inflammatory properties. In this study, paeonol was extracted using a simple water distillation method, and its presence in the distillate was qualitatively confirmed. The extract's antioxidant capacity was evaluated by measuring DPPH free radical scavenging activity and total antioxidant potential. Additionally, its ability to inhibit UV-induced hemolysis in rabbit erythrocytes and its bacteriostatic effects were assessed. This comprehensive functional analysis of paeonol provides a scientific basis for its potential industrial applications, especially in the pharmaceutical and cosmeceutical sectors.</div></div>","PeriodicalId":8799,"journal":{"name":"Biochemical Systematics and Ecology","volume":"122 ","pages":"Article 105051"},"PeriodicalIF":2.0000,"publicationDate":"2025-06-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochemical Systematics and Ecology","FirstCategoryId":"99","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0305197825001000","RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"BIOCHEMISTRY & MOLECULAR BIOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Paeonia suffruticosa Andrews, a member of the Paeoniaceae family (formerly classified under Ranunculaceae), is a well-known traditional Chinese medicinal plant. Its dried root bark is rich in paeonol, a bioactive compound with notable antioxidant, anti-hemolytic, bacteriostatic, and anti-inflammatory properties. In this study, paeonol was extracted using a simple water distillation method, and its presence in the distillate was qualitatively confirmed. The extract's antioxidant capacity was evaluated by measuring DPPH free radical scavenging activity and total antioxidant potential. Additionally, its ability to inhibit UV-induced hemolysis in rabbit erythrocytes and its bacteriostatic effects were assessed. This comprehensive functional analysis of paeonol provides a scientific basis for its potential industrial applications, especially in the pharmaceutical and cosmeceutical sectors.
丹参中丹皮酚晶体的提取、分离及多方面功能评价
牡丹(Paeonia suffruticosa Andrews)是芍药科(原毛茛科)的一员,是我国著名的传统药用植物。其干燥的根皮富含丹皮酚,这是一种生物活性化合物,具有显著的抗氧化、抗溶血、抑菌和抗炎特性。本研究采用简单的水蒸馏法提取丹皮酚,并对其在馏出物中的存在进行定性验证。通过测定提取物对DPPH自由基的清除能力和总抗氧化潜力来评价提取物的抗氧化能力。此外,还对其抑制紫外线诱导的兔红细胞溶血的能力和抑菌作用进行了评估。对丹皮酚的综合功能分析为其潜在的工业应用,特别是在制药和药妆领域的应用提供了科学依据。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
Biochemical Systematics and Ecology
Biochemical Systematics and Ecology 生物-进化生物学
CiteScore
3.00
自引率
12.50%
发文量
147
审稿时长
43 days
期刊介绍: Biochemical Systematics and Ecology is devoted to the publication of original papers and reviews, both submitted and invited, in two subject areas: I) the application of biochemistry to problems relating to systematic biology of organisms (biochemical systematics); II) the role of biochemistry in interactions between organisms or between an organism and its environment (biochemical ecology). In the Biochemical Systematics subject area, comparative studies of the distribution of (secondary) metabolites within a wider taxon (e.g. genus or family) are welcome. Comparative studies, encompassing multiple accessions of each of the taxa within their distribution are particularly encouraged. Welcome are also studies combining classical chemosystematic studies (such as comparative HPLC-MS or GC-MS investigations) with (macro-) molecular phylogenetic studies. Studies that involve the comparative use of compounds to help differentiate among species such as adulterants or substitutes that illustrate the applied use of chemosystematics are welcome. In contrast, studies solely employing macromolecular phylogenetic techniques (gene sequences, RAPD studies etc.) will be considered out of scope. Discouraged are manuscripts that report known or new compounds from a single source taxon without addressing a systematic hypothesis. Also considered out of scope are studies using outdated and hard to reproduce macromolecular techniques such as RAPDs in combination with standard chemosystematic techniques such as GC-FID and GC-MS.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信