Towards trustworthiness of precision medicine research for people with disabilities

IF 31.7 1区生物学 Q1 GENETICS & HEREDITY

Nature genetics Pub Date : 2025-06-02 DOI:10.1038/s41588-025-02195-1

Alejandra Aguirre, Sandra Soo-Jin Lee, Shawneequa Callier, Paul Spicer, Maya Sabatello

引用次数: 0

Abstract

People with disabilities are under-represented in general (non-disability-specific) precision medicine research (PMR), limiting access to its benefits. We examine key reasons for this, focusing on the role of (dis)trust, and identify areas for further inquiry to guide researchers and enhance PMR’s trustworthiness for people with disabilities.

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迈向残疾人精准医学研究的可信赖性

残疾人在一般（非针对残疾的）精准医学研究（PMR）中的代表性不足，限制了获得其利益的机会。我们研究了造成这种情况的关键原因，重点关注（不信任）的作用，并确定了进一步研究的领域，以指导研究人员并提高PMR对残疾人的可信度。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Nature genetics 生物-遗传学

CiteScore

43.00

自引率

2.60%

发文量

241

审稿时长

3 months

期刊介绍： Nature Genetics publishes the very highest quality research in genetics. It encompasses genetic and functional genomic studies on human and plant traits and on other model organisms. Current emphasis is on the genetic basis for common and complex diseases and on the functional mechanism, architecture and evolution of gene networks, studied by experimental perturbation. Integrative genetic topics comprise, but are not limited to: -Genes in the pathology of human disease -Molecular analysis of simple and complex genetic traits -Cancer genetics -Agricultural genomics -Developmental genetics -Regulatory variation in gene expression -Strategies and technologies for extracting function from genomic data -Pharmacological genomics -Genome evolution