DNA and mRNA vaccines: Significant therapeutic approach against cancer management.

3区医学 Q2 Medicine

Advances in Immunology Pub Date : 2025-01-01 Epub Date: 2024-12-10 DOI:10.1016/bs.ai.2024.10.007

Aniruddha Sen, Vijay Singh, Sumel Ashique, Jagriti, Sombuddha Biswas, Anas Islam, Iman Ehsan, Naheed Mojgani

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引用次数: 0

Abstract

Cancer's complex nature and personal variety make it among the toughest cancers to conquer. Innovative treatment strategies can be achieved through new biotechnology developments. DNA and mRNA vaccinations deliver an opportunity to take a new path for cancer. The ways in which DNA and mRNA vaccinations generate immune reactions that specifically focus on cancer cells are discussed in this section. This chapter focuses on the development and creation of these vaccines. We will focus on the latest research that proves the effectiveness of these vaccines and their safety over different types of cancer. Also, we discuss the technological and biological barriers in the process of vaccine development that hinder the development of these vaccines, such as the stability of delivery methods and a patient-specific design for vaccines. DNA and mRNA vaccinations are an important therapeutic approach against cancer with genetic information. They offer an opportunity for the future to develop tailored as well as more efficient treatment options.

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DNA和mRNA疫苗：对癌症管理的重要治疗方法

巨蟹座复杂的天性和多变的个性使其成为最难征服的癌症之一。创新的治疗策略可以通过新的生物技术发展来实现。DNA和mRNA疫苗接种为癌症提供了一条新的途径。本节将讨论DNA和mRNA疫苗接种产生特异性针对癌细胞的免疫反应的方式。本章的重点是这些疫苗的开发和创造。我们将重点关注证明这些疫苗的有效性及其对不同类型癌症的安全性的最新研究。此外，我们还讨论了疫苗开发过程中阻碍这些疫苗开发的技术和生物障碍，例如递送方法的稳定性和疫苗的患者特异性设计。DNA和mRNA疫苗接种是利用遗传信息治疗癌症的重要手段。它们为未来开发量身定制且更有效的治疗方案提供了机会。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Advances in Immunology 医学-免疫学

CiteScore

9.90

自引率

0.00%

发文量

期刊介绍： Advances in Immunology has provided students and researchers with the latest information in Immunology for over 50 years. You can continue to rely on Advances in Immunology to provide you with critical reviews that examine subjects of vital importance to the field through summary and evaluation of current knowledge and research. The articles stress fundamental concepts, but also evaluate the experimental approaches.