Research hotspots and trends in lung cancer immunotherapy are revealed by a bibliometric study spanning the years 2004 to 2024.

IF 3.5 4区 医学 Q2 BIOTECHNOLOGY & APPLIED MICROBIOLOGY
Human Vaccines & Immunotherapeutics Pub Date : 2025-12-01 Epub Date: 2025-05-31 DOI:10.1080/21645515.2025.2512654
Xu Sun, Hongxia Cheng, Jing Zhao, Zhihui Jia, Qiong Xu
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引用次数: 0

Abstract

To summarize the research status of lung cancer immunotherapy using bibliometrics. CiteSpace software was used to analyze all literature on lung cancer immunotherapy collected from the Web of Science (WOS) database from 2004 to 2024. A total of 1702 publications on lung cancer immunotherapy were searched, and the number of articles increased more rapidly after 2014. Two areas intensively studied by the discipline are tumor microenvironment and dendritic cells. He, Jie, Chinese Academy of Medical Sciences - Peking Union Medical College, and China of America were the authors, institutions, and countries with the most. The research trajectory in the use of immunotherapy for lung cancer is thoroughly examined in this article. With tumor microenvironment, blockade, nivolumab, resistance, and chemotherapy being the primary research hotspots. Future studies might concentrate on melanoma, antibody, dendritic cells, non-small cell lung cancer, and ctla 4 blockade.

通过2004年至2024年的文献计量学研究,揭示了肺癌免疫治疗的研究热点和趋势。
综述文献计量学对肺癌免疫治疗的研究现状。采用CiteSpace软件对2004 - 2024年从Web of Science (WOS)数据库中收集的所有肺癌免疫治疗文献进行分析。共检索到肺癌免疫治疗相关文献1702篇,2014年后文献数量增长较快。该学科集中研究的两个领域是肿瘤微环境和树突细胞。何、洁、中国医学科学院-北京协和医学院和中国美国是作者、机构和国家最多的。本文对肺癌免疫治疗的研究轨迹进行了全面的探讨。肿瘤微环境、阻断、纳武单抗、耐药、化疗是主要研究热点。未来的研究可能集中在黑色素瘤、抗体、树突状细胞、非小细胞肺癌和ctla 4阻断上。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Human Vaccines & Immunotherapeutics
Human Vaccines & Immunotherapeutics BIOTECHNOLOGY & APPLIED MICROBIOLOGY-IMMUNOLOGY
CiteScore
7.90
自引率
8.30%
发文量
489
审稿时长
3-6 weeks
期刊介绍: (formerly Human Vaccines; issn 1554-8619) Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer’s and addiction. Many of these vaccines and immunotherapeutics should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines and immunotherapeutics. Human Vaccines & Immunotherapeutics provides such a forum. It is published monthly in a format that is accessible to a wide international audience in the academic, industrial and public sectors.
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