{"title":"Research hotspots and trends in lung cancer immunotherapy are revealed by a bibliometric study spanning the years 2004 to 2024.","authors":"Xu Sun, Hongxia Cheng, Jing Zhao, Zhihui Jia, Qiong Xu","doi":"10.1080/21645515.2025.2512654","DOIUrl":null,"url":null,"abstract":"<p><p>To summarize the research status of lung cancer immunotherapy using bibliometrics. CiteSpace software was used to analyze all literature on lung cancer immunotherapy collected from the Web of Science (WOS) database from 2004 to 2024. A total of 1702 publications on lung cancer immunotherapy were searched, and the number of articles increased more rapidly after 2014. Two areas intensively studied by the discipline are tumor microenvironment and dendritic cells. He, Jie, Chinese Academy of Medical Sciences - Peking Union Medical College, and China of America were the authors, institutions, and countries with the most. The research trajectory in the use of immunotherapy for lung cancer is thoroughly examined in this article. With tumor microenvironment, blockade, nivolumab, resistance, and chemotherapy being the primary research hotspots. Future studies might concentrate on melanoma, antibody, dendritic cells, non-small cell lung cancer, and ctla 4 blockade.</p>","PeriodicalId":49067,"journal":{"name":"Human Vaccines & Immunotherapeutics","volume":"21 1","pages":"2512654"},"PeriodicalIF":3.5000,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12128669/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Human Vaccines & Immunotherapeutics","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1080/21645515.2025.2512654","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/5/31 0:00:00","PubModel":"Epub","JCR":"Q2","JCRName":"BIOTECHNOLOGY & APPLIED MICROBIOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
To summarize the research status of lung cancer immunotherapy using bibliometrics. CiteSpace software was used to analyze all literature on lung cancer immunotherapy collected from the Web of Science (WOS) database from 2004 to 2024. A total of 1702 publications on lung cancer immunotherapy were searched, and the number of articles increased more rapidly after 2014. Two areas intensively studied by the discipline are tumor microenvironment and dendritic cells. He, Jie, Chinese Academy of Medical Sciences - Peking Union Medical College, and China of America were the authors, institutions, and countries with the most. The research trajectory in the use of immunotherapy for lung cancer is thoroughly examined in this article. With tumor microenvironment, blockade, nivolumab, resistance, and chemotherapy being the primary research hotspots. Future studies might concentrate on melanoma, antibody, dendritic cells, non-small cell lung cancer, and ctla 4 blockade.
期刊介绍:
(formerly Human Vaccines; issn 1554-8619)
Vaccine research and development is extending its reach beyond the prevention of bacterial or viral diseases. There are experimental vaccines for immunotherapeutic purposes and for applications outside of infectious diseases, in diverse fields such as cancer, autoimmunity, allergy, Alzheimer’s and addiction. Many of these vaccines and immunotherapeutics should become available in the next two decades, with consequent benefit for human health. Continued advancement in this field will benefit from a forum that can (A) help to promote interest by keeping investigators updated, and (B) enable an exchange of ideas regarding the latest progress in the many topics pertaining to vaccines and immunotherapeutics.
Human Vaccines & Immunotherapeutics provides such a forum. It is published monthly in a format that is accessible to a wide international audience in the academic, industrial and public sectors.