{"title":"Supercritical carbon dioxide extraction of Polygonum cuspidatum powders: Experiments and modelling","authors":"Min Guo, Ningjie Ruan, Bingxu Yao, Shijie Sheng, Xiaoping Li, Yafeng Zhu, Yukun Liu, Zhen Jiao","doi":"10.1002/cjce.25578","DOIUrl":null,"url":null,"abstract":"<p>In recent years, the natural anticancer components resveratrol and emodin have attracted significant attention. This study employs supercritical carbon dioxide (ScCO<sub>2</sub>) extraction, using ethanol as a cosolvent, to extract resveratrol and emodin from <i>Polygonum cuspidatum</i> powders. Experiments were conducted at temperatures ranging from 308 to 328 K, pressures from 15 to 30 MPa, ethanol contents of 60 to 160 mL/L, and extraction times between 1800 and 7200 s. The maximum extraction yields of resveratrol and emodin were 2.516 and 2.765 mg/g, respectively, under optimal conditions (temperature: 323 K, pressure: 25 MPa, ethanol content: 100 mL/L, extraction time: 3600 s), determined through one-way experiments. Additionally, a mathematical model of the ScCO<sub>2</sub> extraction process was developed. The mass transfer coefficient (<i>K</i><sub>f</sub>) was used as a fitting parameter and the kinetic model, based on mass conservation, was validated with experimental data. The model demonstrated good accuracy, with a low average absolute relative deviation (AARD) of 4.05%. This model provides theoretical support for industrial scaling and process optimization, achieving maximum extraction efficiency while minimizing CO₂ and ethanol consumption, thereby reducing costs and enhancing environmental benefits. Its establishment framework and methodology offer valuable references for optimizing similar ScCO<sub>2</sub> extraction processes.</p>","PeriodicalId":9400,"journal":{"name":"Canadian Journal of Chemical Engineering","volume":"103 7","pages":"3495-3504"},"PeriodicalIF":1.6000,"publicationDate":"2024-12-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Canadian Journal of Chemical Engineering","FirstCategoryId":"5","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/cjce.25578","RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"ENGINEERING, CHEMICAL","Score":null,"Total":0}
引用次数: 0
Abstract
In recent years, the natural anticancer components resveratrol and emodin have attracted significant attention. This study employs supercritical carbon dioxide (ScCO2) extraction, using ethanol as a cosolvent, to extract resveratrol and emodin from Polygonum cuspidatum powders. Experiments were conducted at temperatures ranging from 308 to 328 K, pressures from 15 to 30 MPa, ethanol contents of 60 to 160 mL/L, and extraction times between 1800 and 7200 s. The maximum extraction yields of resveratrol and emodin were 2.516 and 2.765 mg/g, respectively, under optimal conditions (temperature: 323 K, pressure: 25 MPa, ethanol content: 100 mL/L, extraction time: 3600 s), determined through one-way experiments. Additionally, a mathematical model of the ScCO2 extraction process was developed. The mass transfer coefficient (Kf) was used as a fitting parameter and the kinetic model, based on mass conservation, was validated with experimental data. The model demonstrated good accuracy, with a low average absolute relative deviation (AARD) of 4.05%. This model provides theoretical support for industrial scaling and process optimization, achieving maximum extraction efficiency while minimizing CO₂ and ethanol consumption, thereby reducing costs and enhancing environmental benefits. Its establishment framework and methodology offer valuable references for optimizing similar ScCO2 extraction processes.
期刊介绍:
The Canadian Journal of Chemical Engineering (CJChE) publishes original research articles, new theoretical interpretation or experimental findings and critical reviews in the science or industrial practice of chemical and biochemical processes. Preference is given to papers having a clearly indicated scope and applicability in any of the following areas: Fluid mechanics, heat and mass transfer, multiphase flows, separations processes, thermodynamics, process systems engineering, reactors and reaction kinetics, catalysis, interfacial phenomena, electrochemical phenomena, bioengineering, minerals processing and natural products and environmental and energy engineering. Papers that merely describe or present a conventional or routine analysis of existing processes will not be considered.