Efficacy of Calcipotriol/Betamethasone Ointment in Facial Discoid Dermatosis

Alberto Murtas, Cristina Mugheddu, Luca Pilloni, Franco Rongioletti, Laura Atzori
{"title":"Efficacy of Calcipotriol/Betamethasone Ointment in Facial Discoid Dermatosis","authors":"Alberto Murtas,&nbsp;Cristina Mugheddu,&nbsp;Luca Pilloni,&nbsp;Franco Rongioletti,&nbsp;Laura Atzori","doi":"10.1002/jvc2.625","DOIUrl":null,"url":null,"abstract":"<p>Facial Discoid Dermatosis (FDD) is a rare chronic skin condition characterised by persistent, annular erythematous and desquamative papules on the face. Its aetiology is unclear, making differential diagnosis challenging. Key clinical features include pink-orange, minimally scaling lesions limited to the face, sudden onset with long-term stability, and resistance to treatment. We report a new case of FDD in a patient in his late 30's, unresponsive to various treatments until improvement with topical calcipotriol/betamethasone ointment. A review of 22 cases reveals a female predominance and broad age range. Histopathology consistently shows hyperkeratosis, parakeratosis, acanthosis, psoriasiform hyperplasia, follicular plugging, and perivascular lymphocytic infiltrate. Many cases, including ours, also reported the presence of abundant Demodex folliculorum.</p>","PeriodicalId":94325,"journal":{"name":"JEADV clinical practice","volume":"4 2","pages":"544-551"},"PeriodicalIF":0.0000,"publicationDate":"2025-02-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/jvc2.625","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"JEADV clinical practice","FirstCategoryId":"1085","ListUrlMain":"https://onlinelibrary.wiley.com/doi/10.1002/jvc2.625","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0

Abstract

Facial Discoid Dermatosis (FDD) is a rare chronic skin condition characterised by persistent, annular erythematous and desquamative papules on the face. Its aetiology is unclear, making differential diagnosis challenging. Key clinical features include pink-orange, minimally scaling lesions limited to the face, sudden onset with long-term stability, and resistance to treatment. We report a new case of FDD in a patient in his late 30's, unresponsive to various treatments until improvement with topical calcipotriol/betamethasone ointment. A review of 22 cases reveals a female predominance and broad age range. Histopathology consistently shows hyperkeratosis, parakeratosis, acanthosis, psoriasiform hyperplasia, follicular plugging, and perivascular lymphocytic infiltrate. Many cases, including ours, also reported the presence of abundant Demodex folliculorum.

钙化三醇/倍他米松软膏治疗面部盘状皮肤病的疗效观察
面部盘状皮肤病(FDD)是一种罕见的慢性皮肤病,其特征是面部持续出现环状红斑和脱屑丘疹。其病因尚不清楚,使得鉴别诊断具有挑战性。主要的临床特征包括粉红色的橙色,局限于面部的最小鳞屑病变,突然发作,长期稳定,对治疗有抵抗力。我们报告一例新的FDD病例,患者年近40岁,对各种治疗无反应,直到局部使用钙化三醇/倍他米松软膏改善。对22例病例的回顾显示,女性居多,年龄范围广。组织病理学一致表现为角化过度、角化不全、棘层增生、银屑病样增生、滤泡堵塞和血管周围淋巴细胞浸润。许多病例,包括我们的病例,也报告了大量毛囊蠕形螨的存在。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
0.30
自引率
0.00%
发文量
0
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:604180095
Book学术官方微信