El impacto del enfoque multidisciplinar en la elección del tratamiento y los resultados del carcinoma urotelial: una revisión sistemática

IF 1.2 4区医学 Q3 UROLOGY & NEPHROLOGY

Actas urologicas espanolas Pub Date : 2025-06-01 DOI:10.1016/j.acuro.2025.501718

E. Albers Acosta , L. Pelari-Mici , G. Celada Luis , C. Velasco Balanza , A. Zapatero , N. Romero-Laorden , P. Toquero Diez , J. Caño-Velasco , F. Guerrero-Ramos , M. Moschini , W. Krajewski , F. Del Giudice , F. Soria , E. Laukhtina , L. Mertens , R. Pichler , K. Mori , D. D’Andrea , A. Mari , G. Marcq , L. San José Manso

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引用次数: 0

Abstract

Introduction and objectives

Urothelial carcinoma is a challenging disease that requires a comprehensive approach. Multidisciplinary tumor committees are essential to bring specialists together, optimize treatment, ensure individualized care, and promote evidence-based decision making. This study aims to collect evidence and explore the impact of multidisciplinary tumor committees in the management of urothelial carcinoma.

Materials and methods

A systematic review was performed following PRISMA guidelines. We searched PubMed/Medline, Embase, Scopus and Cochrane databases for relevant studies on the role of multidisciplinary committees in the management of urothelial carcinoma, including bladder cancer, upper tract urothelial carcinoma and urethral carcinoma. Given the limited and heterogeneous evidence, a systematic review with narrative synthesis was performed.

Results

Multidisciplinary tumor committees had a significant impact on the diagnosis and treatment of urothelial neoplasms, especially bladder cancer. Consistent findings showed that these committees produced substantial changes in treatment, improved adherence to clinical guidelines, and demonstrated a potential to improve patient outcomes. In addition, multidisciplinary committees increased the likelihood of curative treatments and were associated with reduced mortality rates, enhanced clinical decision making, and improved patient care, particularly in bladder and upper tract urothelial carcinoma.

Conclusions

This review highlights the essential role of multidisciplinary tumor committees in improving the management of urothelial carcinoma of the bladder and upper urinary tract. However, further research using standardized approaches is needed. The absence of studies on urethral carcinoma underlines the urgent need to investigate the potential benefits of multidisciplinary tumor committees. Future studies should cover a wider range of tumor types and follow standardized methodologies to provide a more complete and generalizable picture.

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多学科方法对输尿管癌治疗选择和结果的影响：系统综述

导言和目的尿路上皮癌是一种具有挑战性的疾病，需要综合治疗。多学科肿瘤委员会对于汇集专家、优化治疗、确保个体化护理和促进循证决策至关重要。本研究旨在收集证据并探讨多学科肿瘤委员会对尿路上皮癌管理的影响。材料和方法按照PRISMA指南进行系统评价。我们检索PubMed/Medline、Embase、Scopus和Cochrane数据库，查找多学科委员会在尿路上皮癌（包括膀胱癌、上尿道尿路上皮癌和尿道癌）治疗中作用的相关研究。鉴于有限和异质性的证据，进行了系统的综述与叙事综合。结果多学科肿瘤委员会对尿路上皮肿瘤特别是膀胱癌的诊断和治疗具有重要影响。一致的研究结果表明，这些委员会在治疗方面产生了实质性的变化，提高了对临床指南的依从性，并显示出改善患者预后的潜力。此外，多学科委员会增加了治愈性治疗的可能性，并与降低死亡率、加强临床决策和改善患者护理有关，特别是在膀胱和上尿路尿路上皮癌中。结论本综述强调了多学科肿瘤委员会在改善膀胱和上尿路尿路上皮癌治疗中的重要作用。然而，需要使用标准化方法进行进一步的研究。尿道癌研究的缺失强调了迫切需要调查多学科肿瘤委员会的潜在益处。未来的研究应涵盖更广泛的肿瘤类型，并遵循标准化的方法，以提供更完整和可概括的图像。

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来源期刊

Actas urologicas espanolas UROLOGY & NEPHROLOGY-

CiteScore

1.90

自引率

0.00%

发文量

审稿时长

46 days

期刊介绍： Actas Urológicas Españolas is an international journal dedicated to urological diseases and renal transplant. It has been the official publication of the Spanish Urology Association since 1974 and of the American Urology Confederation since 2008. Its articles cover all aspects related to urology. Actas Urológicas Españolas, governed by the peer review system (double blinded), is published online in Spanish and English. Consequently, manuscripts may be sent in Spanish or English and bidirectional free cost translation will be provided.